Rchr
J-GLOBAL ID：201801008935935899
Update date: Apr. 11, 2024
Uehara Osamu
ウエハラ オサム | Uehara Osamu
Affiliation and department：
Homepage URL (1)：
https://www.hoku-iryo-u.ac.jp/course-guide/course/dent/hoken-eisei/top/
Research field (3)：
Surgical dentistry
, Conservative dentistry and endodontics
, Community dentistry
Research keywords (2)：
口腔衛生学
, 予防歯科学
Research theme for competitive and other funds (14)：
- 2023 - 2026 歯髄細胞の歯根膜細胞への分化誘導に関わるエクソソームの網羅的解析
- 2022 - 2025 フィトケミカル含有食品エゾウコギによる、新しいNAFLD/NASH治療法の開発
- 2022 - 2025 女性の歯周疾患に対するMicrobiome・RNA-Seq診断と治療戦略
- 2022 - 2025 エピジェネティクスおよび細菌叢解析に基づくOral Aging Clockの開発
- 2021 - 2024 口腔がんエピゲノム異常遺伝子の網羅的解析とエピゲノム薬による腫瘍抑制効果の検証
- 2020 - 2023 口腔内病原菌内毒素により誘発される膵臓のエピジェネティクス変化
- 2019 - 2022 Metagenomic analysis of mothers and newborns to determine periodontal treatment strategies for the development of healthy gastrointestinal microflora.
- 2018 - 2021 Elucidation of the onset mechanism of autoimmune uveitis caused by endotoxin derived from periodontopathic bacteria
- 2017 - 2020 Genome-wide analysis of epigenetic modification in hippocampus by oral pathogen endotoxin
- 2017 - 2020 Elucidation of the carcinogenic mechanism for the prevention of oral cancer caused by betel quid chewing
- 2017 - 2020 Metagenomic approach in the investigation of oral microbial communities associated with the Behcet's desease
- 2015 - 2018 Development of hop beverages to control dental plaque
- 2015 - 2018 Comprehensive epigenetic analysis on pancreas by periodontal pathogenic bacteria
- 2014 - 2017 Establishment of dental pulp preservation therapy using histone deacetylase inhibitor
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Papers (50)：
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Sarita Giri, Ayuko Takada, Durga Paudel, Osamu Uehara, Yoshihito Kurashige, Yasuhiro Kuramitsu, Masae Furukawa, Kenji Matsushita, Toshiya Arakawa, Toshiyuki Nagasawa, et al. Oral infection with Porphyromonas gingivalis augmented gingival epithelial barrier molecules alteration with aging. Journal of Oral Biosciences. 2024. 66. 1. 126-133
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Durga Paudel, Osamu Uehara, Sarita Giri, Tetsuro Morikawa, Koki Yoshida, Takao Kitagawa, Dedy Ariwansa, Nisha Acharya, Kazunori Ninomiya, Yasuhiro Kuramitsu, et al. Transcriptomic analysis of the submandibular gland under psychological stress condition. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. 2024. 53. 2. 150-158
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Yutaka Kawano, Maki Tanaka, Yasushi Satoh, Shigekazu Sugino, Jun Suzuki, Masaki Fujishima, Eri Okumura, Hideo Takekoshi, Osamu Uehara, Shintaro Sugita, et al. Acanthopanax senticosus ameliorates steatohepatitis through HNF4 alpha pathway activation in mice. Scientific Reports. 2024. 14. 1. 110-110
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Nodoka Sugiyama, Osamu Uehara, Yutaka Kawano, Durga Paudel, Tetsuro Morikawa, Norihiro Nakamoto, Satsuki Kato, Tetsuji Takayama, Toshiyuki Nagasawa, Hiroko Miura, et al. Ingenuity pathway analysis of gingival epithelial cells stimulated with estradiol and progesterone. Journal of Oral Biosciences. 2023. 66. 1. 26-34
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Osamu Uehara, Norihiro Nakamoto, Daichi Hiraki, Durga Paudel, Nodoka Sugiyama, Tetsuro Morikawa, Koki Yoshida, Yutaka Kawano, Tsuyoshi Shimo, Yasushi Furuichi, et al. Effects of prolonged stimulation with heated tobacco products (Ploom TECH+ ) on gingival epithelial cells. Journal of periodontal research. 2023. 58. 3. 553-563
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MISC (24)：
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杉山 のどか, 中本 規裕, 森川 哲郎, パウデル・ドゥルガ, 植原 治, 加藤 幸紀, 安彦 善裕, 古市 保志. 卵巣摘出マウスにおけるエストロゲンおよびプロゲステロン投与の口腔細菌叢への影響. 北海道医療大学歯学雑誌. 2023. 42. 1. 1-8
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植原 治, 安彦 善裕, 三浦 宏子, 長澤 敏行. 唾液の新型コロナウイルスワクチンによって変化するマイクロバイオームの探索. 8020: はち・まる・にい・まる. 2023. 22. 153-155
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森川 哲郎, 中本 規裕, 杉山 のどか, 平木 大地, 原田 文也, 植原 治, 古市 保志, 安彦 善裕. NAFLDモデルマウスの口腔内および腸内細菌叢に対するホップの影響. 北海道医療大学歯学雑誌. 2022. 41. 2. 59-69
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Yutaka Kawano, Jun-ichi Yoshida, Fumiya Harada, Osamu Uehara, Yoshihiro Abiko, Hiroki Nagayasu, Takeo Maida, Tomofumi Kawakami, Yuichiro Eguchi. Elucidating the effect humanoid robot (Pepper) on promoting the hepatitis virus tests. Kanzo. 2022. 63. 8. 388-391
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植原 治. 電子タバコと歯周組織のDNAメチル化 : 老化への影響. 上原記念生命科学財団研究報告集. 2022. 36. 1-4
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Patents (2)：
Books (2)：
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Sirtuin Biology in Cancer and Metabolic Disease: Cellular Pathways for Clinical Discovery
Academic Press 2021 ISBN:0128224673
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Advances in oral tissue engineering
Quintessence Pub. 2014 ISBN:0867156481
Education (2)：
- 2009 - 2013 Health Sciences University of Hokkaido Graduate School of Dentistry Dentistry
- 2002 - 2008 Health Sciences University of Hokkaido School of Dentistry Department of Dentistry
Professional career (1)：
Work history (5)：
- 2021/04 - Health Sciences University of Hokkaido School of Dentistry
- 2013/04 - 2021/03 Health Sciences University of Hokkaido School of Dentistry
- 2019/04 - 2020/03 ブリティッシュコロンビア大学 歯学部 客員研究員
- 2009/04 - 2013/03 Health Sciences University of Hokkaido
- 2008/04 - 2009/03 Health Sciences University of Hokkaido
Committee career (1)：
- 2021/05 - 現在 日本口腔衛生学会 査読委員
Association Membership(s) (4)：
International Association for Dental Research
, 日本口腔衛生学会
, 日本歯周病学会
, 日本歯科保存学会
