Rchr
J-GLOBAL ID:201801009187573250   Update date: Nov. 13, 2023

Furukohri Asako

フルコオリ アサコ | Furukohri Asako
Affiliation and department:
Research field  (2): Molecular biology ,  Genetics
Research keywords  (7): 複製再構成系 ,  DNA二重鎖切断 ,  分子生物学 ,  生化学 ,  DNA損傷 ,  DNA修復 ,  DNA複製
Research theme for competitive and other funds  (5):
  • 2019 - 2023 MRNによる相同組換え開始機構の生化学的解析
  • 2017 - 2019 ヒトMRNの動的構造解析が明らかにするDNA二本鎖切断修復の分子メカニズム
  • 2016 - 2019 DNA二本鎖切断修復機構で働くヒトMre11複合体の酵素活性とその制御機構の解析
  • 2013 - 2015 DNA高次構造が制御するMre11 complexの新規DNA切断活性の解析
  • 2009 - 2010 複製フォークにおける損傷乗り越えDNA合成機構の解析
Papers (19):
  • Sijia Liu, Akira Shinohara, Asako Furukohri. Fanconi anemia-associated mutation in RAD51 compromises the coordinated action of DNA binding and ATPase activities. Journal of Biological Chemistry. 2023. 105424-105424
  • Masaru Ito, Asako Furukohri, Kenichiro Matsuzaki, Yurika Fujita, Atsushi Toyoda, Akira Shinohara. FIGNL1 AAA+ ATPase remodels RAD51 and DMC1 filaments in pre-meiotic DNA replication and meiotic recombination. Nature Communications. 2023. 14. 1
  • Priyanka Sawant, Stephen Mwaniki, Yurika Fujita, Masaru Ito, Asako Furukohri, Akira Shinohara. The role of conserved amino acid residues of Sae3 in Mei5-Sae3 complex for Dmc1 assembly in meiotic recombination. Genes & genetic systems. 2023. 98. 1. 45-52
  • Lan Anh Thi Le, Phooi Yee Chang, Sayaka Ando, Thomas M Conrad, Shohei Nunose, Akiko Sakai, Haruka Uefune, Asako Furukohri, Masahiro Tatsumi Akiyama, Hisaji Maki. Nutritional conditions and oxygen concentration affect spontaneous occurrence of homologous recombination events but not spontaneous mutagenesis in Escherichia coli. Genes & genetic systems. 2020. 95. 2. 85-93
  • Hisashi Tatebe, Chew Theng Lim, Hiroki Konno, Kazuhiro Shiozaki, Akira Shinohara, Takayuki Uchihashi, Asako Furukohri. Rad50 zinc hook functions as a constitutive dimerization module interchangeable with SMC hinge. Nature communications. 2020. 11. 1. 370-370
more...
Professional career (1):
  • 博士(理学) (大阪大学)
Work history (2):
  • 2018/01 - 現在 Osaka University Institute for Protein Research
  • 2009/01 - 2017/12 Nara Institute of Science and Technology Graduate School of Biological Sciences
Awards (1):
  • 2020 - 日本遺伝学会 日本遺伝学会奨励賞
Association Membership(s) (3):
日本生化学会 ,  日本分子生物学会 ,  日本遺伝学会
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