Research field (5)：
Environmental and pharmaceutical development resources
, Pharmaceuticals - chemistry and drug development
, Animals: biochemistry, physiology, behavioral science
, Laboratory animal science
, Pharmacology
Research keywords (3)：
Cuprizone
, Demyelination
, Multiple sclerosis
Research theme for competitive and other funds (1)：
2024 - 2027 ULC-PUFAsによる脱髄治療戦略
Papers (16)：
Ryo Kawabata, Shinji Yamamoto, Nana Kamimura, Ikuko Yao, Keisuke Yoshikawa, Kohei Koga. Cuprizone-induced demyelination provokes abnormal intrinsic properties and excitatory synaptic transmission in the male mouse anterior cingulate cortex. Neuropharmacology. 2025. 271. 110403-110403
Shinji Yamamoto, Kensuke Iwasa, Anzu Yamagishi, Chikara Haruta, Kei Maruyama, Keisuke Yoshikawa. Microglial depletion exacerbates axonal damage and motor dysfunction in mice with cuprizone-induced demyelination. Journal of Pharmacological Sciences. 2023. 153. 3. 94-103
Kensuke Iwasa, Sosuke Yagishita, Nan Yagishita-Kyo, Anzu Yamagishi, Shinji Yamamoto, Kota Yamashina, Chikara Haruta, Masashi Asai, Kei Maruyama, Kuniyoshi Shimizu, et al. Long term administration of loquat leaves and their major component, ursolic acid, attenuated endogenous amyloid-β burden and memory impairment. Scientific Reports. 2023. 13. 1
Kensuke Iwasa, Anzu Yamagishi, Shinji Yamamoto, Chikara Haruta, Kei Maruyama, Keisuke Yoshikawa. GPR137 Inhibits Cell Proliferation and Promotes Neuronal Differentiation in the Neuro2a Cells. Neurochemical Research. 2022. 48. 3. 996-1008
Kota Yamashina, Shinji Yamamoto, Masako Matsumoto, Kensuke Iwasa, Nonoka Takeda, Chikara Haruta, Kei Maruyama, Kuniyoshi Shimizu, Keisuke Yoshikawa. Suppressive Effect of Fruiting Bodies of Medicinal Mushrooms on Demyelination and Motor Dysfunction in a Cuprizone-Induced Multiple Sclerosis Mouse Model. International Journal of Medicinal Mushrooms. 2022. 24. 9. 15-24
