Research field (1)：
Pharmaceuticals - chemistry and drug development
Research theme for competitive and other funds (6)：
2019 - 2022 Elucidation of tip growth factor of fungi and construction of screeing system for antifungal agents
2013 - 2016 Development of biosensor for evaluation of irreversible enzyme inhibitor and application of the sensor for screening of the reagents
2008 - 2010 通電式計測システムによる微量重金属イオンの特異的分析
2007 - 2008 Development of Biosensing system based on the enzyme swiching mechanism and the application of the system
2004 - 2005 Development of a flow type of current application measuring system armed with specific capture and detectability for heavy metal ions
2003 - 2004 コファクタースイッチング機構を用いた新規酵素活性制御法の開発及びその応用
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Papers (39)：
Mao Hayashi, Yoshinari Wada, Akira Yamamura, Hideki Inoue, Naoya Yamashita, Shigetoshi Ichimura, Yasuhiro Iida. Evaluation of the enzymatic properties of DNA (cytosine-5)-methyltransferase M.ApeKI from archaea in the presence of metal ions. Bioscience, Biotechnology, and Biochemistry. 2024. 88. 10. 1155-1163
Mao Hayashi, Keisuke Sugahara, Akira Yamamura, Yasuhiro Iida. Evaluation of the Properties of the DNA Methyltransferase from Aeropyrum pernix K1. Microbiology spectrum. 2021. e0018621
Akiyama Yoshiho, Hasebe Yusuke, Saito Takanobu, Takamura Takeji, Iida Yasuhiro. Development of Yeast Two Hybrid system for screening of apoptosis-inducing anti-tumor reagent. 2022. 46. 41-48
吉川僚汰, 前田翔大, 高村岳樹, 高村岳樹, 飯田泰広, 飯田泰広. Novel methylation analysis method with use of recombinant maintenance methyltransferase. 神奈川工科大学研究報告 B 理工学編(CD-ROM). 2021. 45
Screening of melanin synthesis inhibitory activity on Chinese herbal extracts using B16 melanoma cells
(BioMolecular Horizons 2024)
Functional evaluation of DNMT1 deletion mutant and construction of the expression system for the recombinant DNMT1
(BioMolecular Horizons 2024)
Analysis of the mechanism of action of b-eudesmol in promoting hyaluronan synthase 2(HAS2) expression
(BioMolecular Horizons 2024)
Isolation and purification of tip growth inhibitors in Schizonepeta spike extract with use of yeast vesicular transport evaluation system
(BioMolecular Horizons 2024)
Evaluation of the catalytic activity of thermostable DNA (cytosine-5)-methyltransferase M.ApeKI variants
(BioMolecular Horizons 2024)
