Rchr
J-GLOBAL ID:201801014905970266
Update date: Sep. 12, 2025
SEKINE Hidekazu
セキネ ヒデカズ | SEKINE Hidekazu
Affiliation and department:
Job title:
Associate Professor
Homepage URL (1):
http://scholar.google.com/citations?user=PoSl7loAAAAJ
Research field (1):
Cell biology
Research keywords (6):
リンパ管再生
, Bioreactor
, 血管新生
, 心筋再生
, 組織工学
, 再生医療
Research theme for competitive and other funds (19):
- 2025 - 2029 血管網神経網つき次世代型心臓ペースメーカオルガノイドの開発と応用
- 2024 - 2029 Next generation of regenerative therapies for the treatment of severe heart failure: the creation of a biological heart-assist device
- 2025 - 2028 Engineering 3D tissues with enhanced oxidative stress resistance inspired by hibernation mechanisms
- 2022 - 2025 Development of bio-pulsating ureter using self-organizing collagen tube
- 2022 - 2025 低温灌流培養と血管網付膵島β細胞シートを用いた立体的膵島β細胞組織構築法の確立
- 2022 - 2025 低温灌流培養と血管網付膵島β細胞シートを用いた立体的膵島β細胞組織構築法の確立
- 2022 - 2025 Development of bio-pulsating ureter using self-organizing collagen tube
- 2021 - 2024 Establishment of a pancreas-like tissue construction method using pancreatic islet beta cell sheets with vascular endothelial network
- 2020 - 2023 Development of artificial lymphatic tissue that enables homeostasis of microenvironment
- 2019 - 2023 Creation of functional heart tissues with perfusable vasculature using in vivo prevascularization techniques
- 2019 - 2023 Development of innovative human tumor models using cell patch method for high-speed three-dimensional organization
- 2019 - 2022 高速な3次元組織化を実現する細胞パッチ法を利用した革新的ヒト腫瘍モデルの創製
- 2019 - 2022 インビボプリバスキュラリゼーションによる血管付き高機能心筋組織の創製
- 2019 - 2020 微小環境の恒常性維持を目指した3次元毛細リンパ管組織の創製
- 2014 - 2019 細胞シート工学を基盤とした革新的立体臓器製造技術の開発
- 2014 - 2017 In vitro fabrication of Human heart tissue model with perfusable blood vessels
- 2014 - 2017 ヒト3次元心筋組織モデルの作製
- 2009 - 2014 再生医療産業化に向けたシステムインテグレーション-臓器ファクトリーの創生-
- 2009 - 2010 補助ポンプ型心筋組織の再生
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Papers (75):
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Karthikeyan Thirugnanam, Farhan Rizvi, Arshad Jahangir, Peter Homar, Fathima Shabnam, Sean P Palecek, Suresh N Kumar, Amy Pan, Xiaowen Bai, Hidekazu Sekine, et al. SNRK facilitates cardiac repair associated with nonischemic fibrosis: regulating transforming growth factor-beta1 levels in atrial cardiomyocytes. Regenerative medicine reports. 2025. 2. 2. 45-52
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Junko Katagiri, Jun Homma, Ryo Takagi, Hidekazu Sekine, Takeshi Shinkawa, Hiroshi Niinami, Tatsuya Shimizu. Intravenous mesenchymal stem cell transplantation mitigates pulmonary vascular remodeling but poses dose related risks in a pulmonary veno-occlusive disease model. Stem cell research & therapy. 2025. 16. 1. 258-258
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Katsuhisa Sakaguchi, Kazuki Nakazono, Kodai Tahara, Yuto Hinata, Yusuke Tobe, Jun Homma, Hidekazu Sekine, Katsuhisa Matsuura, Kiyotaka Iwasaki, Satoshi Tsuneda, et al. Cardiomyocyte sheet stacking using fibrin enables high-speed construction of three-dimensional myocardial tissue and high transplantation efficiency. Biofabrication. 2025. 17. 3
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Misako Katsuura, Jun Homma, Yuhei Higashi, Hidekazu Sekine, Tatsuya Shimizu. Author Correction: Densely vascularized thick 3D tissue shows enhanced protein secretion constructed with intermittent positive pressure. Communications biology. 2025. 8. 1. 388-388
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Hiroaki Shidei, Ryo Takagi, Shota Mitsuboshi, Hidekazu Sekine, Tatsuya Shimizu, Masato Kanzaki. Allogeneic fibroblast sheets prevent pulmonary air leaks caused by rat pleural defects without adhesion to the thoracic wall. Regenerative therapy. 2025. 28. 394-401
more...
MISC (213):
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武田直也, 久保田太輝, 加藤大智, 後居洋介, 大木岳志, 大木岳志, 高木亮, 吉田杏美, 本間順, 関根秀一, et al. 高い隆起を長時間維持できるESD粘膜下注入材としての木質バイオマス由来高分子材料の応用. 人工臓器(日本人工臓器学会). 2024. 53. 2
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久保田太輝, 菅川真由香, 加藤大智, 後居洋介, 伊藤圭樹, 大木岳志, 大木岳志, 高木亮, 吉田杏美, 本間順, et al. Functional properties and performance of TOCN gel as submucosal injection material in endoscopic submucosal dissection surgeries of living gastrointestinal tissues. セルロース学会年次大会講演要旨集. 2023. 30th
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久保田太輝, 菅川真由香, 加藤大智, 後居洋介, 伊藤圭樹, 大木岳志, 大木岳志, 高木亮, 吉田杏美, 本間順, et al. Functional and dynamic in vivo analyses of cellulose nanofiber gel as submucosal injection material in ESD surgery. 日本バイオマテリアル学会大会予稿集(Web). 2023. 45th
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佐藤陸翔, 佐藤陸翔, 坂口勝久, 坂口勝久, 戸部友輔, 戸部友輔, 本間順, 関根秀一, 岩崎清隆, 岩崎清隆, et al. 培養下における血管内皮細胞の機能評価. 人工臓器(日本人工臓器学会). 2023. 52. 2
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坂口勝久, 本間順, 関根秀一, 松浦勝久, 岩崎清隆, 清水達也. フィブリンを用いて積層した3次元心筋細胞シートの移植効率の向上. 人工臓器(日本人工臓器学会). 2023. 52. 2
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Patents (12):
Education (1):
- 2001 - 2003 International University of Health and Welfare
Professional career (1):
Work history (3):
- 2022/11 - 現在 Tokyo Women's Medical University Institute of Advanced Biomedical Engineering and Science Associate Professor
- 2013/04 - 2022/10 Tokyo Women's Medical University
- 2008/10 - 2013/03 Tokyo Women's Medical University Institute of Advanced Biomedical Engineering and Science Research Assistant Professor
Committee career (2):
- 2014/11 - 現在 日本再生医療学会 代議員
- 2012/08 - 2014/10 日本再生医療学会 評議員
Awards (3):
- 2011/03 - 日本再生医療学会 第3回 日本再生医療学会 Young Investigator's Award 基礎研究部門優秀賞
- 2010/09 - Tissue Engineering & Regenerative Medicine International Society Asia pacific Best Poster Award
- 2005/07 - 日本炎症・再生医学会 第26回 日本炎症・再生医学会 発表優秀演題
Association Membership(s) (1):
THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE
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