Research theme for competitive and other funds (9)：
2024 - 2027 Optimization of H12-(ADP)-liposome administration in cardiovascular surgery patients
2023 - 2026 羊水塞栓症病態の解明と治療法の検討
2022 - 2025 NETs targeting treatment for consumptive coagulopathy using H12-ADP-liposome
2019 - 2022 Treatment of trauma induced coagulopathy with H12-ADP-liposome
2019 - 2022 Efficacy of Infusion with Hemoglobin Vesicles in Rabbits with Massive obstetric Hemorrhage
2016 - 2019 Combination therapy using fibrinogen gamma-chain peptide-coated, ADP-encapsulated liposomes and hemoglobin vesicles for trauma-induced massive hemorrhage
2016 - 2018 Can a natural amino acid be used for diagnosis and treatment for arteriosclerosis
2013 - 2016 Management against surgical stress in compromised hosts
2013 - 2016 The Novel Hemostatic and Tissue Protective Treatment Elucidating the Pathophysiology of Blast Lung Injury
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Papers (55)：
Koki Kaneko, Kohsuke Hagisawa, Manabu Kinoshita, Yuka Ohtsuka, Ruka Sasa, Morihiro Hotta, Daizoh Saitoh, Kimiya Sato, Shinji Takeoka, Katsuo Terui. Early treatment with Fibrinogen γ-chain peptide-coated, ADP-encapsulated Liposomes (H12-(ADP)-liposomes) ameliorates post-partum hemorrhage with coagulopathy caused by amniotic fluid embolism in rabbits. AJOG Global Reports. 2023. 3. 4. 100280-100280
Osamu Ishida, Kohsuke Hagisawa, Nozomu Yamanaka, Hiroyuki Nakashima, Bradley M. Kearney, Koji Tsutsumi, Shinji Takeoka, Manabu Kinoshita. In vitro study on the effect of fibrinogen γ-chain peptide-coated ADP-encapsulated liposomes on postcardiopulmonary bypass coagulopathy using patient blood. Journal of Thrombosis and Haemostasis. 2023. 21. 7. 1934-1942
Kohsuke Hagisawa, Manabu Kinoshita, Shinji Takeoka, Osamu Ishida, Yayoi Ichiki, Daizoh Saitoh, Morihiro Hotta, Masato Takikawa, Ivo P Torres Filho, Yuji Morimoto. H12-(ADP)-liposomes for hemorrhagic shock in thrombocytopenia: Mesenteric artery injury model in rabbits. Research and practice in thrombosis and haemostasis. 2022. 6. 2. e12659
Hiroki Ishibashi, Kohsuke Hagisawa, Manabu Kinoshita, Yukako Yuki, Morikazu Miyamoto, Tomoko Kure, Hiromi Sakai, Daizoh Saitoh, Katsuo Terui, Masashi Takano. Resuscitative efficacy of hemoglobin vesicles for severe postpartum hemorrhage in pregnant rabbits. Scientific reports. 2021. 11. 1. 22367-22367
2001 - 2005 Graduate School of Medicine, National Defense Med Coll
1988 - 1994 National Defense Med Coll
Professional career (1)：
博士(医学) (学位授与機構)
Work history (4)：
2023/04 - 現在 National Defense Medical College Department of Physiology Associate Professor
2011/03 - 2023/03 National Defense Med Coll Department of Physiology Assistant Professor
2008/08 - 2011/03 部隊医学実験隊 研究科 研究科長
2006/07 - 2008/07 自衛隊札幌病院 診療科 第2内科部長
Committee career (2)：
2017/09 - 現在 日本ショック学会 評議員
2014/04 - 現在 日本生理学会 評議員
Awards (8)：
2015/11 - American Heart Association ReSS 2015 YIA
2014/11 - American Heart Association ReSS 2014 YIA
2014/05 - The Japan Shock Society 29th Presidential Award
2013/11 - American Heart Association ReSS 2013 YIA
2008/07 - Ministry of Defense Third Grade Defense Achievement Chapter
2004/02 - 福田記念医療技術振興財団 国際交流助成賞
2003/11 - Japan Heart Foundation 29th Japan Heart Foundation Research Grant
2003/10 - Japanese Society for Medical and Biological Engineering 17th YIA
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Association Membership(s) (6)：
The Japan Shock Society
, THE JAPANESE SOCIETY OF INTERNAL MEDICINE
, THE PHYSIOLOGICAL SOCIETY OF JAPAN
, The Japanese Circulation Society
, American Heart Association
, 日本血液代替物学会
