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J-GLOBAL ID：201801017681501540   Update date: Feb. 01, 2024

Hagisawa Kohsuke

ハギサワ コウスケ | Hagisawa Kohsuke
Affiliation and department：
National Defense Medical College

About National Defense Medical College


Job title： Associate Professor
Other affiliations (1)：
  • National Defense Medical College Hospital  Associate Professor
Research field  (2)： Physiology ,  Cardiology
Research keywords  (6)： coagulopathy ,  hemorrhagic shock ,  ultrasound therapeutics ,  atherosclerosis ,  thrombosis hemostasis ,  Cardiology
Research theme for competitive and other funds  (8)：
  • 2023 - 2026 羊水塞栓症病態の解明と治療法の検討
  • 2022 - 2025 NETs targeting treatment for consumptive coagulopathy using H12-ADP-liposome
  • 2019 - 2022 妊娠家兎を用いた危機的産科出血に対する人工酸素運搬体投与による救命効果の研究
  • 2019 - 2022 Treatment of trauma induced coagulopathy with H12-ADP-liposome
  • 2016 - 2019 Combination therapy using fibrinogen gamma-chain peptide-coated, ADP-encapsulated liposomes and hemoglobin vesicles for trauma-induced massive hemorrhage
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Papers (46)：
  • Koki Kaneko, Kohsuke Hagisawa, Manabu Kinoshita, Yuka Ohtsuka, Ruka Sasa, Morihiro Hotta, Daizoh Saitoh, Kimiya Sato, Shinji Takeoka, Katsuo Terui. Early treatment with Fibrinogen γ-chain peptide-coated, ADP-encapsulated Liposomes (H12-(ADP)-liposomes) ameliorates post-partum hemorrhage with coagulopathy caused by amniotic fluid embolism in rabbits. AJOG Global Reports. 2023. 3. 4. 100280-100280
  • Osamu Ishida, Kohsuke Hagisawa, Nozomu Yamanaka, Hiroyuki Nakashima, Bradley M. Kearney, Koji Tsutsumi, Shinji Takeoka, Manabu Kinoshita. In vitro study on the effect of fibrinogen γ-chain peptide-coated ADP-encapsulated liposomes on postcardiopulmonary bypass coagulopathy using patient blood. Journal of Thrombosis and Haemostasis. 2023. 21. 7. 1934-1942
  • Kohsuke Hagisawa, Manabu Kinoshita, Shinji Takeoka, Osamu Ishida, Yayoi Ichiki, Daizoh Saitoh, Morihiro Hotta, Masato Takikawa, Ivo P Torres Filho, Yuji Morimoto. H12-(ADP)-liposomes for hemorrhagic shock in thrombocytopenia: Mesenteric artery injury model in rabbits. Research and practice in thrombosis and haemostasis. 2022. 6. 2. e12659
  • Hiroki Ishibashi, Kohsuke Hagisawa, Manabu Kinoshita, Yukako Yuki, Morikazu Miyamoto, Tomoko Kure, Hiromi Sakai, Daizoh Saitoh, Katsuo Terui, Masashi Takano. Resuscitative efficacy of hemoglobin vesicles for severe postpartum hemorrhage in pregnant rabbits. Scientific reports. 2021. 11. 1. 22367-22367
  • Yukako Yuki, Kohsuke Hagisawa, Manabu Kinoshita, Hiroki Ishibashi, Kouki Kaneko, Osamu Ishida, Daizoh Saitoh, Hiromi Sakai, Katsuo Terui. Efficacy of Resuscitative Infusion with Hemoglobin Vesicles in Rabbits with Massive Obstetric Hemorrhage. American Journal of Obstetrics and Gynecology. 2021. 224. 398. e1-e11
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MISC (46)：
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Patents (2)：
Lectures and oral presentations  (138)：
  • 人工血液によって出血性ショックと凝固障害を制御する
    (日本外科代謝栄養学会第59回学術集会 2022)
  • 家兎における羊水塞栓症・産科出血モデルの開発とH12ADPリポソームの効果
    (第28回日本血液代替物学会年次大会 シンポジウム4 2021)
  • エンドトキシン血症時の凝固障害に対するH12ADPリポソーム投与効果の検討
    (第28回日本血液代替物学会年次大会 シンポジウム4 2021)
  • 産科危機的出血モデルに対する人工酸素運搬体HbVの効果
    (第28回日本血液代替物学会年次大会 シンポジウム1 2021)
  • 教育講演2 人工赤血球の開発と臨床応用・産科危機的出血モデルへの投与
    (第31回日本産婦人科・新生児血液学会 学術集会 2021)
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Education (2)：
  • 2001 - 2005 Graduate School of Medicine, National Defense Med Coll
  • 1988 - 1994 National Defense Med Coll
Professional career (1)：
  • 博士(医学) (学位授与機構)
Work history (4)：
  • 2023/04 - 現在 National Defense Medical College Department of Physiology Associate Professor
  • 2011/03 - 2023/03 National Defense Med Coll Department of Physiology Assistant Professor
  • 2008/08 - 2011/03 部隊医学実験隊 研究科 研究科長
  • 2006/07 - 2008/07 自衛隊札幌病院 診療科 第2内科部長
Committee career (2)：
  • 2017/09 - 現在 日本ショック学会 評議員
  • 2014/04 - 現在 日本生理学会 評議員
Awards (8)：
  • 2015/11 - American Heart Association ReSS 2015 YIA
  • 2014/11 - American Heart Association ReSS 2014 YIA
  • 2014/05 - The Japan Shock Society 29th Presidential Award
  • 2013/11 - American Heart Association ReSS 2013 YIA
  • 2008/07 - Ministry of Defense Third Grade Defense Achievement Chapter
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Association Membership(s) (6)：
The Japan Shock Society ,  THE JAPANESE SOCIETY OF INTERNAL MEDICINE ,  THE PHYSIOLOGICAL SOCIETY OF JAPAN ,  The Japanese Circulation Society ,  American Heart Association ,  日本血液代替物学会
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