Yasuda Kaori

ヤスダカオリ | Yasuda Kaori

Affiliation and department：

Research field (2)： Nutrition and health science , Pharmaceuticals - health and biochemistry

Research keywords (3)：ビタミンD , Biochemistry , Drug metabolism

Research theme for competitive and other funds (15)：

2024 - 2027 ビタミンDによる抗炎症機構の解明および炎症性腸疾患との関連
2023 - 2026 Synthesis of half-life prolonging vitamin D derivatives and analysis of enhancement of hormone-effects on disease animal models
2022 - 2025 遺伝子疾患動物評価系を用いたビタミンD誘導体の開発および遺伝子治療法の確立
2020 - 2023 循環腫瘍細胞・セルクラスター・セルフリー核酸を調べつくすためのシンプルな分離法
2019 - 2022 Elucidation of vitamin D actions using genetically modified rats and application of vitamin D analogs to medical drugs

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Papers (98)：

Yuichiro Iwai, Ayano Iijima, Satoko Kise, Chika Nagao, Yuto Senda, Kana Yabu, Hiroki Mano, Miyu Nishikawa, Shinichi Ikushiro, Kaori Yasuda, et al. Characterization of Rickets Type II Model Rats to Reveal Functions of Vitamin D and Vitamin D Receptor. Biomolecules. 2023. 13. 11
Satoko Kise, Ayano Iijima, Chika Nagao, Tadashi Okada, Miyu Nishikawa, Shinichi Ikushiro, Tomoko Nakanishi, Shigeto Sato, Kaori Yasuda, Toshiyuki Sakaki. Gene therapy for alopecia in type II rickets model rats using vitamin D receptor-expressing adenovirus vector. Scientific reports. 2023. 13. 1. 18528-18528
岩井悠一郎, 飯島綾乃, 木瀬智子, 岡田只士, 西川美宇, 生城真一, 中西友子, 斎藤泉, 安田佳織, 榊利之. ビタミンD関連遺伝子改変ラットを用いたビタミンD作用メカニズムの解明. 日本生化学会大会プログラム・講演要旨集. 2023. 96回. [1P-356]
Takuya Kushioka, Hiroki Mano, Sayuri Matsuoka, Miyu Nishikawa, Kaori Yasuda, Shinichi Ikushiro, Toshiyuki Sakaki. Analysis of vitamin D metabolites in biological samples using a nanoluc-based vitamin D receptor ligand sensing system: NLucVDR. The Journal of steroid biochemistry and molecular biology. 2023. 233. 106367-106367
Fumihiro Kawagoe, Sayuri Mototani, Kaori Yasuda, Akiko Takeuchi, Hiroki Mano, Shinji Kakuda, Hiroshi Saitoh, Toshiyuki Sakaki, Atsushi Kittaka. Synthesis of (22R)-, (22S)-22-Fluoro-, and 22,22-Difluoro-25-hydroxyvitamin D₃ and Effects of Side-Chain Fluorination on Biological Activity and CYP24A1-Dependent Metabolism. The Journal of Organic Chemistry. 2023

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MISC (120)：

岡本侑樹, 真野寛生, 川越文裕, 高野真史, 西川美宇, 生城真一, 橘高敦史, 榊利之, 安田佳織. 変異型ビタミンD受容体に高い親和性を有する新規誘導体の探索. ビタミン. 2024. 98. 4
本谷小佑里, 川越文裕, 安田佳織, 真野寛生, 榊利之, 橘高敦史. 24,24-ジフルオロ-26,27-ジメチルビタミンD₃誘導体の合成. ビタミン. 2023. 97. 4
岩井悠一郎, 高橋秀, SHARMA Vanshita, 真野寛生, 川越文裕, 高野真史, 橘高敦史, 中西友子, 佐藤栄人, 榊利之, et al. ヒトCYP24A1発現アデノウイルスベクターを用いたビタミンD誘導体代謝予測系の開発. ビタミン. 2023. 97. 4
川越文裕, 本谷小佑里, 安田佳織, 真野寛生, 榊利之, 橘高敦史. 26,27-ジフルオロ-25-ヒドロキシビタミンD₃および26,26,27,27-テトラフルオロ-25-ヒドロキシビタミンD₃の合成. ビタミン. 2023. 97. 4
本谷小佑里, 川越文裕, 安田佳織, 榊利之, 橘高敦史. An efficient introduction of the 22,22-difluoro unit to the CD-ringand synthesis of 22,22-difluoro-25-hydroxyvitamin D₃. 日本薬学会年会要旨集(Web). 2023. 143rd

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Patents (12)：

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Education (3)：

2013 - 2013 Toyama Prefectural University Faculty of Engineering
2002 - 2004 Kyoto University
1998 - 2002 Kyoto University Faculty of Engineering School of Industrial Chemistry

Professional career (1)：

博士(工学) (富山県立大学)

Work history (6)：

2023/04 - 現在 Toyama Prefectural University
2019/04 - 2023/03 Toyama Prefectural University
2017/04 - 2019/03 Toyama Prefectural University Faculty of Engineering
2016/04 - 2017/03 Toyama Prefectural University Faculty of Engineering, Department of Biotechnology
2008/10 - 2016/03 Toyama Prefectural University Faculty of Engineering, Department of Biotechnology

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Awards (5)：

2021/06 - 日本ビタミン学会 2021年度日本ビタミン学会奨励賞天然型ビタミンDおよびビタミンD誘導体の代謝と生理作用に関する研究
2019/05 - 22nd Workshop on Vitamin D Elsevier Poster Award Elucidation of 25-hydroxyvitamin D3 metabolism using Cyp24a1-knockout Rats generated by CRISPR/Cas9 System.
2017/11 - 日本薬物動態学会第32回年会ベストポスター賞 Comparative analysis of 25-hydroxyvitamin D3 metabolism between wild-type and CYP24A1-knockout rats.
2017/09 - Innovation Forums Basel Life 2017 1st prize of the Poster Award 2017 Application of actinomycetes CYP105A1 to the production of active forms of vitamin D or drug metabolites
2015/11 - The 6th International Conference on Food Factors (IcoFF 2015) Young Investigator Award Sesamin metabolism by drug-metabolizing enzymes and drug-sesamin interaction

Association Membership(s) (5)：

THE JAPANESE SOCIETY FOR BIOMATERIALS , THE VITAMIN SOCIETY OF JAPAN , THE JAPANESE BIOCHEMICAL SOCIETY , THE JAPANESE SOCIETY FOR THE STUDY OF XENOBIOTICS , THE PHARMACEUTICAL SOCIETY OF JAPAN

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