Rchr
J-GLOBAL ID:201801018254518225   Update date: Jul. 23, 2021

Kimura Yasuaki

キムラ ヤスアキ | Kimura Yasuaki
Affiliation and department:
Research field  (3): Biochemistry ,  Pharmaceuticals - chemistry and drug development ,  Chemical biology
Research keywords  (3): RNA ,  ケミカルバイオロジー ,  核酸化学
Research theme for competitive and other funds  (3):
  • 2018 - 2020 標的酵素で活性化される共有結合医薬の開発
  • 2016 - 2018 mRNAの化学合成を可能にするRNAライゲーション反応の開発
  • 2010 - 2013 環境調和型触媒的不斉炭素-炭素結合形成反応の開発と重要医薬品合成への応用
Papers (26):
  • Yuki Yoshida, Masakazu Honma, Yasuaki Kimura, Hiroshi Abe. Structure, Synthesis and Inhibition Mechanism of Nucleoside Analogues as HIV-1 Reverse Transcriptase Inhibitors (NRTIs). ChemMedChem. 2021. 16. 5. 743-766
  • Daisuke Kawaguchi, Ayumi Kodama, Naoko Abe, Kei Takebuchi, Fumitaka Hashiya, Fumiaki Tomoike, Kosuke Nakamoto, Yasuaki Kimura, Yoshihiro Shimizu, Hiroshi Abe. Phosphorothioate Modification of mRNA Accelerates the Rate of Translation Initiation to Provide More Efficient Protein Synthesis. Angewandte Chemie International Edition. 2020. 59. 40. 17403-17407
  • Shun Sakuraba, Junichi Iwakiri, Michiaki Hamada, Tomoshi Kameda, Genichiro Tsuji, Yasuaki Kimura, Hiroshi Abe, Kiyoshi Asai. Free-Energy Calculation of Ribonucleic Inosines and Its Application to Nearest-Neighbor Parameters. Journal of chemical theory and computation. 2020
  • Hirotaka Fujita, Ryota Oikawa, Mayu Hayakawa, Fumiaki Tomoike, Yasuaki Kimura, Hiroyuki Okuno, Yoshiki Hatashita, Carolina Fiallos Oliveros, Haruhiko Bito, Toshio Ohshima, et al. Quantification of native mRNA dynamics in living neurons using fluorescence correlation spectroscopy and reduction-triggered fluorescent probes. Journal of Biological Chemistry. 2020. 295. 23. 7923-7940
  • Daisuke Kawaguchi, Saaya Shimizu, Naoko Abe, Fumitaka Hashiya, Fumiaki Tomoike, Yasuaki Kimura, Hiroshi Abe. Translational control by secondary-structure formation in mRNA in a eukaryotic system. Nucleosides, Nucleotides & Nucleic Acids. 2020. 39. 1-3. 195-203
more...
MISC (4):
Education (2):
  • 2008 - 2013 東京大学大学院 分子薬学専攻
  • 2004 - 2008 The University of Tokyo
Professional career (1):
  • 博士(薬学) (東京大学)
Work history (7):
  • 2020/07 - 現在 Nagoya University
  • 2020/07 - 現在 Nagoya University Graduate School of Science
  • 2017/06 - 2020/06 Nagoya University Nagoya University
  • 2015/07 - 2020/06 名古屋大学大学院 理学研究科 助教
  • 2015/04 - 2015/06 東京大学大学院 薬学系研究科 特任助教
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Awards (2):
  • 2018/11 - 日本核酸化学会 大塚賞
  • 2011/10 - 公益財団法人MSD生命科学財団 大津会議アワードフェロー
Association Membership(s) (5):
JAPANESE SOCIETY FOR CHEMICAL BIOLOGY ,  The Japan Society of Nucleic Acids Chemistry ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE CHEMICAL SOCIETY OF JAPAN ,  NUCLEIC ACIDS THERAPEUTICS SOCIETY OF JAPAN
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