Rchr
J-GLOBAL ID：201801020561254671   Update date: Nov. 11, 2024

Taichi Ohshiro

オオシロ タイチ | Taichi Ohshiro
Affiliation and department：
Kitasato University School of Pharmaceutical Sciences

About Kitasato University School of Pharmaceutical Sciences


Homepage URL  (1)： https://www.kitasato-u.ac.jp/pharm/research/laboratory/laboratory-detail/?lab_pk=1669807811
Research field  (2)： Environmental and pharmaceutical development resources ,  Pharmaceuticals - chemistry and drug development
Research keywords  (2)： 脂質代謝 ,  天然物化学
Research theme for competitive and other funds  (6)：
  • 2022 - 2025 トリプルネガティブ乳がん共通のバイオロジーを標的とした新規医薬品の探索
  • 2022 - 2023 薬剤耐性非結核性抗酸菌に対する新規治療薬の開発
  • 2018 - 2023 Collection and utilization of bioresources and natural products from Indonesia
  • 2018 - 2021 中性脂質蓄積制御からの脂肪肝/脂肪肝炎の予防治療薬の開拓
  • 2016 - 2018 微生物資源を用いた中性脂質生成制御からの創薬へのアプローチ
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Papers (72)：
  • Hanaka Satoh, Daiki Lee, Shiho Arima, Kanji Hosoda, Satoru Shigeno, Hiroshi Tomoda, Taichi Ohshiro, Tohru Nagamitsu. Total syntheses of mavintramycin A and its structural analog, cytosaminomycin C, and evaluation of their antibacterial activities against Mycobacterium avium and Mycobacterium intracellulare. Tetrahedron. 2024. 134299-134299
  • Ryuga Matsuta, Satoru Shigeno, Taichi Ohshiro, Masafumi Ueda, Kentaro Takada. Catalindoles A-C: brominated indole alkaloids from the starfish Thromidia catalai, which feeds on Theonella sponges. Fisheries Science. 2024
  • ALIMUDDIN ALI, MUHARRAM PASSITTA, HERLINA RANTE, ELLY WAHYUDIN, NANA JUNIARTI NATSIR DJIDE, ROLAND JANSEN POLITAN, ELYZA AIMAN NUR, SATORU SHIGENO, SATOSHI OHTE, KEISUKE KOBAYASHI, et al. Antibiotic production by an endophytic Streptomyces isolated from the medicinal plant Poikilospermum suaveolens. Biodiversitas Journal of Biological Diversity. 2024. 25. 5. 2221-2229
  • Ryota Okamura, Katsuki Kikuchi, Akito Taniguchi, Kenichiro Nagai, Reiko Seki, Satoshi Ohte, Taichi Ohshiro, Masashi Ando, Teruyoshi Tanaka, Takashi Fukuda. The new seriniquinone glycoside by biological transformation using the deep sea-derived bacterium Bacillus licheniformis KDM612. The Journal of antibiotics. 2024
  • Keisuke Kobayashi, Rio Tejima, Kenichiro Nagai, Reiko Seki, Tsuyoshi Hosoya, Yumi Une, Satoru Shigeno, Hiroshi Tomoda, Taichi Ohshiro. Paranazzamides A and B, new cyclic dipeptides containing a C7-prenylated tryptophan, produced by pathogenic reptile fungi Paranannizziopsis sp. UH-21. The Journal of antibiotics. 2024. 77. 7. 403-411
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MISC (4)：
  • Tumenbayar Bayasgalan, Shuichi Nagashima, Hiroaki Yagyu, Fumiko Tazoe, Ken Ohashi, Manabu Takahashi, Taichi Ohshiro, Motohiro Sekiya, Jun-ichi Osuga, Shun Ishibashi. Macrophage-Specific Disruption of HMG-CoA Reductase Inhibited the Development of Atherosclerosis. CIRCULATION. 2011. 124. 21
  • Taichi Ohshiro, Daisuke Matsuda, Kent Sakai, Chiara Degirolamo, Hiroaki Yagyu, Lawrence L. Rudel, Satoshi Omura, Shun Ishibashi, Hiroshi Tomoda. Pyripyropene A, a Selective Inhibitor of Acyl-CoA:cholesterol Acyltransferase 2, Attenuates Hypercholesterolemia and Atherosclerosis in Murine Models of Hyperlipidemia. CIRCULATION. 2010. 122. 21
  • 松田 大介, 大城 太一, 供田 洋. スタチンを超える薬物療法の可能性 (特集 脂質異常症--基本を踏まえた実践) -- (残された課題). 内科. 2009. 103. 1. 137-140
  • Application to combinatorial synthesis of fungal beauveriolides for drug development. Bio industry. 2007. 24. 7. 39-47
Patents (9)：
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Books (4)：
  • パートナー薬理学
    南江堂 2024 ISBN:9784524404285
  • 化学療法学(改訂第2版): 病原微生物・がんと戦う
    南江堂 2018 ISBN:4524403493
  • 化学系薬学III(スタンダード薬学シリーズII-3): 自然が生み出す薬物
    東京化学同人 2016 ISBN:4807917072
  • 糖尿病の分子標的と治療薬事典〜糖尿病・代謝疾患治療薬のターゲット分子と作用機序,薬効のすべて
    羊土社 2013 ISBN:4758120420
Lectures and oral presentations  (44)：
  • 真菌 Paramyrothecium sp. BF-1049 株が生産する新規抗悪性中皮腫活性物質に関する研究
    (日本薬学会第 144 年会 2024)
  • 海洋由来放線菌 Streptomyces sp. KKMA-0239 株が生産する新規 polycyclic tetramate macrolactam 類化合物に関する研究
    (日本薬学会第 144 年会 2024)
  • 真菌 Talaromyces cellulolytics BF-0307 株が生産する新規イソベンゾフラン化合物に関する研究
    (日本薬学会第 144 年会 2024)
  • Fungal drimane sesquiterpenoids from BF-1613 strain as sterol O-acyltransferase (SOAT) inhibitors
    (日本薬学会第 144 年会 2024)
  • Amphotericin B 活性増強物質 nectriatide 誘導体の合成と活性評価
    (日本薬学会第 144 年会 2024)
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Education (3)：
  • 2004 - 2007 Kitasato University Graduate School of Infectioncontrol Sciences
  • 2002 - 2004 Kitasato University Graduate School of Infectioncontrol Sciences
  • 1998 - 2002 Kitasato University School of Pharmaceutical Sciences Faculty of Pharmaceutical Sciences
Work history (10)：
  • 2021/04 - 現在 Kitasato University School of Pharmacy
  • 2019/06 - 2023/03 Nagoya University Itochu, Graduate School of Medicine
  • 2017/04 - 2019/05 Kitasato University School of Pharmaceutical Sciences
  • 2016/04 - 2017/03 Kitasato University School of Pharmaceutical Sciences
  • 2015/07 - 2016/03 Kitasato University School of Pharmaceutical Sciences
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Awards (1)：
  • 2013 - 北里大学 第29回二宮善基記念賞
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