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J-GLOBAL ID：201802210756403194   Reference number：18A1389141

Metabolome analysis of the serotonin syndrome rat model: Abnormal muscular contraction is related to metabolic alterations and hyper-thermogenesis

セロトニン症候群ラットモデルのメタボローム解析:異常な筋収縮は代謝変化と超熱発生に関連する【JST・京大機械翻訳】

Author (16)： Zaitsu Kei (In Vivo Real-time Omics Laboratory, Institute for Advanced Research, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan) ,  Zaitsu Kei (Department of Legal Medicine & Bioethics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan) ,  Noda Saki (Department of Legal Medicine & Bioethics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan) ,  Iguchi Akira (Marine Geo-Environment Research Group, Institute of Geology and Geoinformation, National Institute of Advanced Industrial Science and Technology (AIST), AIST Tsukuba Central 7, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8567, Japan) ,  Hayashi Yumi (In Vivo Real-time Omics Laboratory, Institute for Advanced Research, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan) ,  Hayashi Yumi (Department of Radiological and Medical Laboratory Sciences, Nagoya University Graduate School of Medicine, 1-1-20 Daiko-Minami, Higashi-ku, Nagoya 461-8673, Japan) ,  Ohara Tomomi (Department of Legal Medicine & Bioethics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan) ,  Kimura Yuya (Department of Legal Medicine & Bioethics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan) ,  Koketsu Yuta (Department of Legal Medicine & Bioethics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan) ,  Kosaki Tomoko (Department of Legal Medicine & Bioethics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan) ,  Kusano Maiko (Department of Legal Medicine & Bioethics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan) ,  Sato Takako (Department of Legal Medicine, Osaka Medical College, Daigakumachi 2-7, Takatsuki City, Osaka 569-8686, Japan) ,  Ishikawa Tetsuya (Department of Radiological and Medical Laboratory Sciences, Nagoya University Graduate School of Medicine, 1-1-20 Daiko-Minami, Higashi-ku, Nagoya 461-8673, Japan) ,  Tsuchihashi Hitoshi (Department of Legal Medicine & Bioethics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan) ,  Suzuki Koichi (Department of Legal Medicine, Osaka Medical College, Daigakumachi 2-7, Takatsuki City, Osaka 569-8686, Japan) ,  Ishii Akira (Department of Legal Medicine & Bioethics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan)
Material： Life Sciences  (Life Sciences including Pharmacology Letters)
Volume： 207  Page： 550-561  Publication year： 2018 
JST Material Number： B0699B  ISSN： 0024-3205  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Serotonin syndrome (SS) is an ...

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Thesaurus term： metabolite ,  Plasma ,  *Metabolism ,  *Rattus ,  biomarker ,  Proteins ,  branched-chain amino acid ,  *Muscle Contraction ,  Up-Regulation ,  amino acid ,  citric acid cycle ,  overexpression ,  *Metabolome ,  *Myomorpha ,  aliphatic alcohol ,  aliphatic carboxylic acid ,  secondary alcohol ,  hydroxy acid
Semi thesaurus term： プロファイリング , 【Automatic Indexing@JST】

Author keywords (5)： Serotonin syndrome ,  Metabolome analysis ,  GC/MS/MS ,  Hyperthermia ,  Abnormal muscular contraction

JST classification (1)： Basic medicine on cardiovascular system  (GJ01020K)

Substance index (1)： Lactic acid

Terms in the title (7)： セロトニン症候群 ,  ラット ,  モデル ,  メタボローム解析 ,  筋収縮 ,  代謝 ,  熱発生