Art

J-GLOBAL ID：201802211865582810   Reference number：18A1346191

Cellular Entry of Clostridium perfringens Iota-Toxin and Clostridium botulinum C2 Toxin

Clostridium perfringensイオタ毒素とClostridium botulinum C2毒素の細胞内侵入【JST・京大機械翻訳】

Author (9)： Takehara Masaya (Department of Microbiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan) ,  Takagishi Teruhisa (Department of Microbiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan) ,  Seike Soshi (Laboratory of Molecular Microbiological Science, Faculty of Pharmaceutical Sciences, Hiroshima International University, Kure, Hiroshima 737-0112, Japan) ,  Oda Masataka (Department of Microbiology and Infection Control Science, Kyoto Pharmaceutical University, Yamashina, Kyoto 607-8414, Japan) ,  Sakaguchi Yoshihiko (Department of Microbiology, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252-0374, Japan) ,  Hisatsune Junzo (Department of Bacteriology, Graduate school of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan) ,  Ochi Sadayuki (Faculty of Pharmacy, Yokohama University of Pharmacy, 601 Matano-cho, Totsuka-ku, Yokohama-shi, Kanagawa 245-0066, Japan) ,  Kobayashi Keiko (Department of Microbiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan) ,  Nagahama Masahiro (Department of Microbiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan)
Material： Toxins (Web)
Volume： 9  Issue： 8  Page： 247  Publication year： 2017 
JST Material Number： U7286A  ISSN： 2072-6651  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Clostridium perfringens iota-t...

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Thesaurus term： enzyme ,  actin ,  Cell Membrane ,  receptor ,  *toxin ,  *Clostridium perfringens ,  Cytosol ,  *Clostridium botulinum ,  oligomerization ,  internalization ,  lipid raft ,  invasion ,  binding protein ,  Actin Cytoskeleton ,  *Clostridium ,  Endomembrane system ,  *microorganism ,  *Spore-Forming Bacteria ,  *Bacillaceae
Semi thesaurus term： *Clostridium , 【Automatic Indexing@JST】

Author keywords (4)： clostridial binary toxin ,  iota-toxin ,  C2 toxin ,  cellular internalization

JST classification (3)： Biological function  (EB03040U) ,  Cell physiology in general  (EF02010S) ,  Toxicity of microorganism derived substances  (GZ03030F)

Reference (50)：

• Gibert, M.; Petit, L.; Raffestin, S.; Okabe, A.; Popoff, M.R. Clostridium perfringens iota-toxin requires activation of both binding and enzymatic components for cytopathic activity. Infect. Immun. 2000, 68, 3848-3853.
• Popoff, M.R.; Boquet, P. Clostridial toxins. Future Microbiol. 2009, 4, 1021-1064.
• Sakurai, J.; Nagahama, M.; Oda, M.; Tsuge, H.; Kobayashi, K. Clostridium perfringens iota-toxin: Structure and function. Toxins 2009, 1, 208-228.
• Stiles, B.G.; Wilkins, T.D. Purification and characterization of Clostridium perfringens iota-oxin: Dependence on two nonlinked proteins for biological activity. Infect. Immun. 1986, 54, 683-688.
• Gülke, I.; Pfeifer, G.; Liese, J.; Fritz, M.; Hofmann, F.; Aktories, K.; Barth, H. Characterization of the enzymatic component of the ADP-ribosyltransferase toxin. CDTa from Clostridium difficile. Infect. Immun. 2001, 69, 6004-6011.

Terms in the title (4)： Clostridium ,  毒素 ,  C2 ,  侵入