Art

J-GLOBAL ID：201802212766235417   Reference number：18A1305944

Lacking ketohexokinase-A exacerbates renal injury in streptozotocin-induced diabetic mice

ケトヘキソキナーゼA欠損はストレプトゾトシン誘発糖尿病マウスにおける腎障害を悪化させる【JST・京大機械翻訳】

Author (15)： Doke Tomohito (Departments of Nephrology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan) ,  Doke Tomohito (Departments of Biochemistry, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan) ,  Ishimoto Takuji (Departments of Nephrology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan) ,  Hayasaki Takahiro (Departments of Nephrology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan) ,  Ikeda Satsuki (Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata 997-0052, Japan) ,  Hasebe Masako (Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata 997-0052, Japan) ,  Hirayama Akiyoshi (Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata 997-0052, Japan) ,  Soga Tomoyoshi (Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata 997-0052, Japan) ,  Kato Noritoshi (Departments of Nephrology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan) ,  Kosugi Tomoki (Departments of Nephrology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan) ,  Tsuboi Naotake (Departments of Nephrology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan) ,  Lanaspa Miguel A. (Division of Renal Diseases and Hypertension, University of Colorado Denver, Aurora, CO 80045, USA) ,  Johnson Richard J. (Division of Renal Diseases and Hypertension, University of Colorado Denver, Aurora, CO 80045, USA) ,  Kadomatsu Kenji (Departments of Biochemistry, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan) ,  Maruyama Shoichi (Departments of Nephrology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan)
Material： Metabolism  (Clinical and Experimental)
Volume： 85  Page： 161-170  Publication year： 2018 
JST Material Number： B0230B  ISSN： 0026-0495  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Ketohexokinase (KHK), a primar...

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Thesaurus term： diabetic nephropathy ,  wild type ,  anoxia ,  Inflammation ,  enzyme ,  glycolysis ,  *Diabetes Mellitus ,  citric acid cycle ,  intraperitoneal administration ,  oxidative stress ,  Metabolism ,  kidney tubule ,  isoform ,  *diabetic mice ,  complication ,  hexose ,  ketose

Author keywords (6)： Diabetic kidney disease ,  Fructose metabolism ,  Ketohexokinase ,  Tubular injury ,  Oxidative stress ,  NAD metabolism

JST classification (1)： Metabolic diseases,nutritional diseases in general.  (GD05010J)

Substance index (1)： Fructose

Terms in the title (6)： 欠損 ,  ストレプトゾトシン ,  誘発 ,  糖尿病マウス ,  腎障害 ,  悪化