Art

J-GLOBAL ID：201802215121645736   Reference number：18A1372321

Plasma Xanthine Oxidoreductase Activity as a Novel Biomarker of Metabolic Disorders in a General Population

一般集団における代謝障害の新規バイオマーカーとしての血漿キサンチン酸化還元酵素活性

Author (12)： Furuhashi Masato (Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine) ,  Matsumoto Megumi (Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine) ,  Tanaka Marenao (Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine) ,  Moniwa Norihito (Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine) ,  Murase Takayo (Sanwa Kagaku Kenkyusho Co., Ltd.) ,  Nakamura Takashi (Sanwa Kagaku Kenkyusho Co., Ltd.) ,  Ohnishi Hirofumi (Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine) ,  Ohnishi Hirofumi (Department of Public Health, Sapporo Medical University School of Medicine) ,  Saitoh Shigeyuki (Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine) ,  Saitoh Shigeyuki (Department of Nursing, Division of Medical and Behavioral Subjects, Sapporo Medical University School of Health Sciences) ,  Shimamoto Kazuaki (Japan Health Care College) ,  Miura Tetsuji (Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine)
Material： Circulation Journal  (Circ J)
Volume： 82  Issue： 7  Page： 1892-1899(J-STAGE)  Publication year： 2018 
JST Material Number： F0908A  ISSN： 1346-9843  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *xanthine oxidase ,...
Semi thesaurus term： *xanthine oxidoreductase

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Author keywords (5)： Insulin resistance ,  Liver dysfunction ,  Obesity ,  Smoking ,  Uric acid

JST classification (1)： Metabolic diseases,nutritional diseases in general.  (GD05010J)

Reference (43)：

• 1. Wu XW, Lee CC, Muzny DM, Caskey CT. Urate oxidase: Primary structure and evolutionary implications. Proc Natl Acad Sci USA 1989; 86: 9412-9416.
• 2. Matsuura F, Yamashita S, Nakamura T, Nishida M, Nozaki S, Funahashi T, et al. Effect of visceral fat accumulation on uric acid metabolism in male obese subjects: Visceral fat obesity is linked more closely to overproduction of uric acid than subcutaneous fat obesity. Metabolism 1998; 47: 929-933.
• 3. Kim TH, Lee SS, Yoo JH, Kim SR, Yoo SJ, Song HC, et al. The relationship between the regional abdominal adipose tissue distribution and the serum uric acid levels in people with type 2 diabetes mellitus. Diabetol Metab Syndr 2012; 4: 3.
• 4. Matsuzawa Y, Funahashi T, Nakamura T. The concept of metabolic syndrome: Contribution of visceral fat accumulation and its molecular mechanism. J Atheroscler Thromb 2011; 18: 629-639.
• 5. Nasr G, Maurice C. Allopurinol and global left myocardial function in heart failure patients. J Cardiovasc Dis Res 2010; 1: 191-195.

Terms in the title (7)： 集団 ,  代謝障害 ,  バイオマーカー ,  血漿 ,  キサンチン ,  酸化還元 ,  酵素活性