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J-GLOBAL ID：201802216786496283   Reference number：18A0359502

Role of hypoxia-inducible factor-1 in the development of renal fibrosis in mouse obstructed kidney: Special references to HIF-1 dependent gene expression of profibrogenic molecules

マウス閉塞腎における腎線維症の進展における低酸素誘導因子-1の役割:特に線維形成誘導性分子のHIF-1依存性遺伝子発現

Author (13)： Kabei Kazuya (Department of Applied Pharmacology and Therapeutics, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka 545-8585, Japan) ,  Kabei Kazuya (Department of Urology, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka 545-8585, Japan) ,  Tateishi Yu (Ishikiri Seiki Hospital, Yayoi-cho, Higashiosaka, Osaka 579-8026, Japan) ,  Nozaki Masakazu (Department of Applied Pharmacology and Therapeutics, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka 545-8585, Japan) ,  Tanaka Masako (Department of Applied Pharmacology and Therapeutics, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka 545-8585, Japan) ,  Tanaka Masako (Department of Life Science and Medical BioScience, School of Advanced Science and Engineering, Waseda University, Wakamatsu-cho, Shinjuku-ku, Tokyo, 162-8480, Japan) ,  Shiota Masayuki (Department of Research Support Platform, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka 545-8585, Japan) ,  Osada-Oka Mayuko (Food Hygiene and Environmental Health, Division of Applied Life Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Sakyo-ku, Kyoto 606-8522, Japan) ,  Nishide Shunji (Department of Urology, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka 545-8585, Japan) ,  Uchida Junji (Department of Urology, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka 545-8585, Japan) ,  Nakatani Tatsuya (Department of Urology, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka 545-8585, Japan) ,  Tomita Shuhei (Department of Pharmacology, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka 545-8585, Japan) ,  Miura Katsuyuki (Department of Applied Pharmacology and Therapeutics, Osaka City University Graduate School of Medicine, Asahimachi, Abeno-ku, Osaka 545-8585, Japan)
Material： Journal of Pharmacological Sciences (Web)  (J Pharmacol Sci (Web))
Volume： 136  Issue： 1  Page： 31-38  Publication year： 2018 
JST Material Number： U0667A  ISSN： 1347-8613  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *kidney disease ,...
Semi thesaurus term： *HIF1 ,...

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Author keywords (4)： Hypoxia-inducible factor ,  Hypoxia ,  Renal fibrosis ,  HIF-1α

JST classification (1)： Basic medicine on urogenital system  (GM01020T)

Substance index (1)： Tamoxifen

Reference (38)：

• Fine LG, Norman JT. Chronic hypoxia as a mechanism of progression of chronic kidney diseases: from hypothesis to novel therapeutics. Kidney Int. 2008;74:867-872.
• Schofield CJ, Ratcliffe PJ. Oxygen sensing by HIF hydroxylases. Nat Rev Mol Cell Biol. 2004;5:343-354.
• Matsumoto M, Makino Y, Tanaka T, et al. Induction of renoprotective gene expression by cobalt ameliorates ischemic injury of the kidney in rats. J Am Soc Nephrol. 2003;14:1825-1832.
• Bernhardt WM, Campean V, Kany S, et al. Preconditional activation of hypoxiainducible factors ameliorates ischemic acute renal failure. J Am Soc Nephrol. 2006;17:1970-1978.
• Hill P, Shukla D, Tran MG, et al. Inhibition of hypoxia inducible factor hydroxylases protects against renal ischemia-reperfusion injury. J Am Soc Nephrol. 2008;19:39-46.

Terms in the title (12)： マウス ,  閉塞 ,  腎 ,  腎線維症 ,  進展 ,  低酸素誘導因子 ,  役割 ,  線維形成 ,  分子 ,  HIF-1 ,  依存性 ,  遺伝子発現