Art
J-GLOBAL ID：201802217121886493   Reference number：18A0713346

Formulation of a poorly water-soluble drug in sustained-release hollow granules with a high viscosity water-soluble polymer using a fluidized bed rotor granulator

流動層ロータグラニュレータを用いた高粘度水溶性高分子による徐放性中空顆粒中の難水溶性薬物の処方【JST・京大機械翻訳】
Author (6)：
Asada Takumi

About Asada Takumi

(Sumitomo Dainippon Pharma Co., Ltd., 3-45 Kurakakiuchi 1-chome, Ibaraki-shi, Osaka 567-0878, Japan)

About Sumitomo Dainippon Pharma Co., Ltd., 3-45 Kurakakiuchi 1-chome, Ibaraki-shi, Osaka 567-0878, Japan

, 
Yoshihara Naoki

About Yoshihara Naoki

(School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan)

About School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan

, 
Ochiai Yasushi

About Ochiai Yasushi

(Sumitomo Dainippon Pharma Co., Ltd., 3-45 Kurakakiuchi 1-chome, Ibaraki-shi, Osaka 567-0878, Japan)

About Sumitomo Dainippon Pharma Co., Ltd., 3-45 Kurakakiuchi 1-chome, Ibaraki-shi, Osaka 567-0878, Japan

, 
Kimura Shin-ichiro

About Kimura Shin-ichiro

(School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan)

About School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan

, 
Iwao Yasunori

About Iwao Yasunori

(School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan)

About School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan

, 
Itai Shigeru

About Itai Shigeru

(School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan)

About School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan


Material：
International Journal of Pharmaceutics  (Int J Pharm)

About International Journal of Pharmaceutics


Volume： 541  Issue： 1-2  Page： 246-252  Publication year： 2018 
JST Material Number： A0285B  ISSN： 0378-5173  CODEN： IJPHD  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)
Abstract/Point：
Abstract/Point
Japanese summary of the article(about several hundred characters).
All summary is available on JDreamIII(charged).
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Water-soluble polymers with hi...
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Thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
polymer

About polymer

, 
*granule (particle)

About granule (particle)

, 
delayed action preparation

About delayed action preparation

, 
*water solubility

About water solubility

, 
*water-soluble polymer

About water-soluble polymer

, 
drug release

About drug release

, 
*coefficient of viscosity

About coefficient of viscosity

, 
particle size (ratio)

About particle size (ratio)

, 
dissolution

About dissolution

, 
blood concentration

About blood concentration

, 
*fluidized bed

About fluidized bed

, 
granulation

About granulation

, 
particle size distribution

About particle size distribution

, 
dosage form

About dosage form

, 
*sustained release

About sustained release

, 
*coefficient

About coefficient

, 
*transport coefficient

About transport coefficient

, 
*degree

About degree


Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
*難溶性薬物

About 難溶性薬物

, 【Automatic Indexing@JST】
Author keywords (6)：
Granulation

About Granulation

, 
Rotary fluidized bed granulator

About Rotary fluidized bed granulator

, 
Controlled release

About Controlled release

, 
Hollow spherical particle

About Hollow spherical particle

, 
High drug-loaded granule

About High drug-loaded granule

, 
Tablet

About Tablet

JST classification (2)：
JST classification
Category name(code) classified by JST.
Basic biopharmacy 
(GY01021U)

About Basic biopharmacy

,  Solid preparations 
(GY02030V)

About Solid preparations

Terms in the title (8)：
Terms in the title
Keywords automatically extracted from the title.
流動層

About 流動層

, 
高粘度

About 高粘度

, 
水溶性高分子

About 水溶性高分子

, 
徐放性

About 徐放性

, 
中空

About 中空

, 
顆粒

About 顆粒

, 
難水溶性薬物

About 難水溶性薬物

, 
処方

About 処方


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