Art

J-GLOBAL ID：201802217297227220   Reference number：18A0017807

Nivolumab in patients with advanced gastric or gastro-oesophageal junction cancer refractory to, or intolerant of, at least two previous chemotherapy regimens (ONO-4538-12, ATTRACTION-2): a randomised, double-blind, placebo-controlled, phase 3 trial

または不耐性難治性進行性胃癌あるいは胃食道接合部癌患者におけるニボルマブ,少なくとも2以前の化学療法レジメン(ONO 4538 12, ATTRACTION 2):無作為化二重盲検プラセボ対照第3相試験【Powered by NICT】

Author (25)： Kang Yoon-Koo (Department of Oncology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea) ,  Boku Narikazu (Division of Gastrointestinal Medical Oncology, National Cancer Center Hospital, Tokyo, Japan) ,  Satoh Taroh (Frontier Science for Cancer and Chemotherapy, Osaka University Graduate School of Medicine, Suita, Japan) ,  Ryu Min-Hee (Department of Oncology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea) ,  Chao Yee (Department of Oncology, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Kato Ken (Division of Gastrointestinal Medical Oncology, National Cancer Center Hospital, Tokyo, Japan) ,  Chung Hyun Cheol (Division of Medical Oncology, Medical Oncology Yonsei Cancer Center, Song-Dang Institute for Cancer Research, Yonsei University College of Medicine, Yonsei University Health System, Seoul, South Korea) ,  Chen Jen-Shi (Division of Hematology and Oncology, Department of Internal Medicine, Linkou Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan) ,  Muro Kei (Department of Clinical Oncology, Aichi Cancer Center Hospital, Nagoya, Japan) ,  Kang Won Ki (Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea) ,  Yeh Kun-Huei (Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan) ,  Yoshikawa Takaki (Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan) ,  Oh Sang Cheul (Division of Hematology and Oncology, Department of Internal Medicine, College of Medicine, Korea University, Seoul, South Korea) ,  Bai Li-Yuan (Division of Hematology and Oncology, Department of Internal Medicine, China Medical University Hospital, China Medical University, Taichung, Taiwan) ,  Tamura Takao (Department of Medical Oncology, Faculty of Medicine, Kindai University, Osakasayama, Japan) ,  Lee Keun-Wook (Division of Hematology and Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea) ,  Hamamoto Yasuo (Keio Cancer Center, Keio University School of Medicine, Tokyo, Japan) ,  Kim Jong Gwang (Kyungpook National University School of Medicine, Daegu, South Korea) ,  Chin Keisho (Department of Gastroenterology, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, Japan) ,  Oh Do-Youn (Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea) ,  Minashi Keiko (Department of Clinical Trial Promotion, Chiba Cancer Center, Chiba, Japan) ,  Cho Jae Yong (Department of Medical Oncology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea) ,  Tsuda Masahiro (Department of Gastroenterological Oncology, Hyogo Cancer Center, Akashi, Japan) ,  Chen Li-Tzong (National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan) ,  Chen Li-Tzong (National Cheng Kung University Hospital, National Cheng Kung University, Tainan, Taiwan)
Material： Lancet
Volume： 390  Issue： 10111  Page： 2461-2471  Publication year： 2017 
JST Material Number： B0673A  ISSN： 0140-6736  CODEN： LANCA  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Patients with advanced gastric...

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Thesaurus term： evaluation criterion ,  human ,  Japan ,  Republic of Korea ,  *placebo ,  *phase 3 study ,  toxicity ,  *double blind test ,  *patient ,  *drug therapy ,  monoclonal antibody ,  Safety ,  *Advanced gastric cancer ,  adverse reaction
Semi thesaurus term： 有害事象 ,  *食道胃接合部癌 , 【Automatic Indexing@JST】

JST classification (1)： Drug therapy(=pharmacotherapy)for tumors  (GE03032C)

Terms in the title (11)： 耐性 ,  進行性胃癌 ,  胃食道接合部癌 ,  患者 ,  ニボルマブ ,  化学療法 ,  レジメン ,  二重盲検 ,  プラセボ ,  対照 ,  第3相試験