Art

J-GLOBAL ID：201802217636199896   Reference number：18A1154304

Treatment of intermittent hypoxia increases phosphorylated tau in the hippocampus via biological processes common to aging

間欠性低酸素症の治療は加齢に共通の生物学的プロセスを介して海馬におけるリン酸化タウを増加させる【JST・京大機械翻訳】

Author (13)： Yagishita Sosuke (Department of Pharmacology, Faculty of Medicine, Saitama Medical University, Iruma-gun, Japan) ,  Yagishita Sosuke (Present address: Department of Peripheral Nervous System Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Japan) ,  Suzuki Seiya (Department of Pharmacology, Faculty of Medicine, Saitama Medical University, Iruma-gun, Japan) ,  Suzuki Seiya (Faculty of Health and Medical Care, Saitama Medical University, Hidaka-shi, Japan) ,  Yoshikawa Keisuke (Department of Pharmacology, Faculty of Medicine, Saitama Medical University, Iruma-gun, Japan) ,  Iida Keiko (Department of Genomic Drug Discovery Science, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Japan) ,  Hirata Ayako (Department of Genomic Drug Discovery Science, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Japan) ,  Suzuki Masahiko (Department of Pharmacology, Faculty of Medicine, Saitama Medical University, Iruma-gun, Japan) ,  Suzuki Masahiko (Faculty of Health and Medical Care, Saitama Medical University, Hidaka-shi, Japan) ,  Takashima Akihiko (Department of Life Science, Faculty of Science, Gakushuin University, Toshima-ku, Japan) ,  Maruyama Kei (Department of Pharmacology, Faculty of Medicine, Saitama Medical University, Iruma-gun, Japan) ,  Hirasawa Akira (Department of Genomic Drug Discovery Science, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Japan) ,  Awaji Takeo (Department of Pharmacology, Faculty of Medicine, Saitama Medical University, Iruma-gun, Japan)
Material： Molecular Brain (Web)
Volume： 10  Issue： 1  Page： 2  Publication year： 2017 
JST Material Number： U7335A  ISSN： 1756-6606  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Sleep-disordered breathing pro...

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Thesaurus term： *Eumetopias jubata ,  Alzheimer Disease ,  Biotechnology ,  sleep disorder ,  *phosphorylation ,  risk factor ,  protocol ,  *anoxia ,  gene ,  gene expression ,  Proteins ,  database ,  *therapy ,  Cognition Disorders ,  molecular genetic phenomenon ,  ether ,  macrocyclic compound ,  lactam ,  lactone ,  enzyme inhibitor ,  hemiacetal ,  alicyclic alcohol ,  secondary alcohol ,  hydroxy ketone

Author keywords (5)： Sleep-disordered breathing ,  Intermittent hypoxia ,  Gene ontology-based microarray analysis ,  Alzheimer disease ,  Tau

JST classification (2)： Central nervous system  (EJ12030F) ,  Basic psychiatry  (GR01020I)

Substance index (1)： Sirolimus

Reference (81)：

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Terms in the title (8)： 間欠性 ,  低酸素症 ,  治療 ,  加齢 ,  生物学 ,  プロセス ,  海馬 ,  リン酸化