CIRCADIAN OSCILLATION IN THE INTESTINAL EXPRESSION OF OCTN1/SLC22A4 UNDERLIES THE DOSING TIME-DEPENDENT CHANGES IN THE ABSORPTION OF PREGABALIN AND ITS ANALGESIC EFFECTS ON DIABETIC NEUROPATHY

KOYANAGI Satoru; AKAMINE Takahiro; WADA Erika; KUSUNOSE Naoki; TANIGUCHI Marie; MATSUNAGA Naoya; OHDO Shigehiro

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J-GLOBAL ID：201802222110842302 Reference number：18A0463402

CIRCADIAN OSCILLATION IN THE INTESTINAL EXPRESSION OF OCTN1/SLC22A4 UNDERLIES THE DOSING TIME-DEPENDENT CHANGES IN THE ABSORPTION OF PREGABALIN AND ITS ANALGESIC EFFECTS ON DIABETIC NEUROPATHY

OCTN1/SLC22A4の腸発現の概日振動は糖尿病性ニューロパチーに対するプレガバリン吸収およびその鎮痛効果における用量時間依存性変化の基礎となる

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Material：
Volume： 32 Issue： 1 Supplement Page： S89 (WEB ONLY) Publication year： Jan. 2017
JST Material Number： U0705A ISSN： 1347-4367 Document type： Article
Article type：会議録記事 Country of issue： Netherlands (NLD) Language： ENGLISH (EN)

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Basic biopharmacy , Basic research of antipyretic analgesics , Basic neurology , Gene expression

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