Art

J-GLOBAL ID：201802226096279027   Reference number：18A1336424

Detoxification Mechanism of α,β-Unsaturated Carbonyl Compounds in Cigarette Smoke Observed in Sheep Erythrocytes

ヒツジ赤血球で観察されたタバコ煙中のα,β-不飽和カルボニル化合物の解毒機構

Author (9)： Horiyama Shizuyo (Mukogawa Women’s University, Institute for Bioscience) ,  Horiyama Shizuyo (School of Pharmacy and Pharmaceutical Sciences, Mukogawa Women’s University) ,  Hatai Mayuko (School of Pharmacy and Pharmaceutical Sciences, Mukogawa Women’s University) ,  Ichikawa Atsushi (Mukogawa Women’s University, Institute for Bioscience) ,  Ichikawa Atsushi (School of Pharmacy and Pharmaceutical Sciences, Mukogawa Women’s University) ,  Yoshikawa Noriko (Mukogawa Women’s University, Institute for Bioscience) ,  Yoshikawa Noriko (School of Pharmacy and Pharmaceutical Sciences, Mukogawa Women’s University) ,  Nakamura Kazuki (School of Pharmacy and Pharmaceutical Sciences, Mukogawa Women’s University) ,  Kunitomo Masaru (School of Pharmacy and Pharmaceutical Sciences, Mukogawa Women’s University)
Material： Chemical and Pharmaceutical Bulletin (Web)
Volume： 66  Issue： 7  Page： 721-726(J-STAGE)  Publication year： 2018 
JST Material Number： U1401A  ISSN： 1347-5223  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *aerosol (suspended solids) ,...
Semi thesaurus term： *cigarette smoke

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Author keywords (8)： cigarette smoke extract (CSE) ,  glutathione (GSH) ,  epalrestat ,  αβ-unsaturated carbonyl compound ,  cigarette smoke extract (CSE) ,  glutathione (GSH) ,  epalrestat ,  αβ-unsaturated carbonyl compound

JST classification (1)： Basic research of other drugs acting on metabolism  (GW13060I)

Substance index (5)： Acrolein ,  1-Penten-3-one ,  Epalrestat ,  Glutathione ,  Crotonaldehyde

Reference (26)：

• 1) Ezzati M., Lopez A. D., Lancet, 362, 847-852 (2003).
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• 3) Takahashi Y., Horiyama S., Kimoto Y., Yoshikawa N., Kunitomo M., Kagota S., Shinozuka K., Nakamura K., Pharmacol. Pharm., 3, 316-321 (2012).
• 4) Horiyama S., Takahashi Y., Hatai M., Honda C., Suwa K., Ichikawa A., Yoshikawa N., Nakamura K., Kunitomo M., Date S., Masujima T., Takayama M., Chem. Pharm. Bull., 62, 772-778 (2014).
• 5) Kaminskas L. M., Pyke S. M., Burcham P. C., Chem. Res. Toxicol., 18, 1627-1633 (2005).

Terms in the title (6)： ヒツジ赤血球 ,  観察 ,  タバコ煙 ,  不飽和 ,  カルボニル化合物 ,  解毒