Art

J-GLOBAL ID：201402263184562467   Reference number：14A0957140

Methyl Vinyl Ketone, a Toxic Ingredient in Cigarette Smoke Extract, Modifies Glutathione in Mouse Melanoma Cells

たばこの煙の抽出物中の毒性物質であるメチルビニルケトンはマウスメラノーマ細胞においてグルタチオンを修飾する

Author (13)： HORIYAMA Shizuyo (School of Pharmacy and Pharmaceutical Sciences, Mukogawa Women’s Univ.) ,  TAKAHASHI Yuta (School of Pharmacy and Pharmaceutical Sciences, Mukogawa Women’s Univ.) ,  TAKAHASHI Yuta (Dep. of Pharmacy, Gunma Univ. Hospital) ,  HATAI Mayuko (School of Pharmacy and Pharmaceutical Sciences, Mukogawa Women’s Univ.) ,  HONDA Chie (School of Pharmacy and Pharmaceutical Sciences, Mukogawa Women’s Univ.) ,  SUWA Kiyoko (School of Pharmacy and Pharmaceutical Sciences, Mukogawa Women’s Univ.) ,  ICHIKAWA Atsushi (School of Pharmacy and Pharmaceutical Sciences, Mukogawa Women’s Univ.) ,  YOSHIKAWA Noriko (School of Pharmacy and Pharmaceutical Sciences, Mukogawa Women’s Univ.) ,  NAKAMURA Kazuki (School of Pharmacy and Pharmaceutical Sciences, Mukogawa Women’s Univ.) ,  KUNITOMO Masaru (School of Pharmacy and Pharmaceutical Sciences, Mukogawa Women’s Univ.) ,  DATE Sachiko (Riken Quantitative Biology Center, OLABB, Osaka Univ.) ,  MASUJIMA Tsutomu (Riken Quantitative Biology Center, OLABB, Osaka Univ.) ,  TAKAYAMA Mitsuo (International Graduate School of Arts and Sciences, Yokohama City Univ.)
Material： Chemical and Pharmaceutical Bulletin  (Chemical & Pharmaceutical Bulletin)
Volume： 62  Issue： 8  Page： 772-778 (J-STAGE)  Publication year： 2014 
JST Material Number： G0504A  ISSN： 0009-2363  CODEN： CPBTAL  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *aerosol (suspended solids) ,...
Semi thesaurus term： *cigarette smoke ,...

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JST classification (2)： Toxicity of plant derived substances  (GZ03010J) ,  Influence on animals  (EE05040R)

Substance index (3)： Glutathione ,  Crotonaldehyde ,  Methyl vinyl ketone

Reference (25)：

• 1) Ezzati M., Lopez A. D., Lancet, 362, 847-852 (2003).
• 2) Hoffmann D., Hoffmann I., El-Bayoumy K., Chem. Res. Toxicol., 14, 767-790 (2001).
• 3) Aoshiba K., Nagai A., Tob. Induc. Dis., 1, 219-226 (2003).
• 4) Fearon I. M., Faux S. P., J. Mol. Cell. Cardiol., 47, 372-381 (2009).
• 5) Tuder R. M., Petrache I., J. Clin. Invest., 122, 2749-2755 (2012).

Terms in the title (8)： たばこの煙 ,  抽出物 ,  毒性物質 ,  メチルビニルケトン ,  マウス ,  メラノーマ細胞 ,  グルタチオン ,  修飾