Art

J-GLOBAL ID：201802227073140235   Reference number：18A0854237

CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes

CALHM3はGPCR仲介性のtastの迅速なイオンチャネル仲介プリン作動性神経伝達に必須である【JST・京大機械翻訳】

Author (23)： Ma Zhongming (Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA) ,  Taruno Akiyuki (Department of Molecular Cell Physiology, Kyoto Prefectural University of Medicine, Kyoto, Japan) ,  Ohmoto Makoto (Monell Chemical Senses Center, Philadelphia, PA, USA) ,  Jyotaki Masafumi (Monell Chemical Senses Center, Philadelphia, PA, USA) ,  Lim Jason C. (Department of Anatomy and Cell Biology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA) ,  Miyazaki Hiroaki (Department of Molecular Cell Physiology, Kyoto Prefectural University of Medicine, Kyoto, Japan) ,  Niisato Naomi (Department of Molecular Cell Physiology, Kyoto Prefectural University of Medicine, Kyoto, Japan) ,  Marunaka Yoshinori (Department of Molecular Cell Physiology, Kyoto Prefectural University of Medicine, Kyoto, Japan) ,  Marunaka Yoshinori (Department of Bio-Ionomics, Kyoto Prefectural University of Medicine, Kyoto, Japan) ,  Lee Robert J. (Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA) ,  Lee Robert J. (Department of Otorhinolaryngology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA) ,  Hoff Henry (Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA) ,  Payne Riley (Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA) ,  Demuro Angelo (Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA, USA) ,  Parker Ian (Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA, USA) ,  Mitchell Claire H. (Department of Anatomy and Cell Biology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA) ,  Henao-Mejia Jorge (Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA) ,  Tanis Jessica E. (Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA) ,  Tanis Jessica E. (Department of Biological Sciences, University of Delaware, Newark, DE, USA) ,  Matsumoto Ichiro (Monell Chemical Senses Center, Philadelphia, PA, USA) ,  Tordoff Michael G. (Monell Chemical Senses Center, Philadelphia, PA, USA) ,  Foskett J. Kevin (Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA) ,  Foskett J. Kevin (Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA)
Material： Neuron
Volume： 98  Issue： 3  Page： 547-561.e10  Publication year： 2018 
JST Material Number： T0649A  ISSN： 0896-6273  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Binding of sweet, umami, and b...

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Thesaurus term： umami ,  *neural transmission ,  complex(substance) ,  sense of taste ,  interaction ,  subunit ,  patch-clamp ,  sweetness ,  bitterness ,  *ion channel ,  electric potential ,  *channel
Semi thesaurus term： 共発現 ,  電位依存性 ,  *G蛋白質共役型受容体 , 【Automatic Indexing@JST】

Author keywords (10)： ATP release ,  voltage-gated ,  taste bud ,  hexamer ,  single-molecule photobleaching ,  blue-native page ,  concatemer ,  patch-clamp electrophysiology ,  mouse ,  knockout

JST classification (2)： Transport of cell membrane  (EF04020R) ,  Cell physiology in general  (EF02010S)

Terms in the title (5)： GPCR ,  仲介 ,  イオンチャネル ,  プリン ,  神経伝達