Art

J-GLOBAL ID：201802232302104833   Reference number：18A0556931

High Sensitivity and Precision High-Temperature Reversed-Phase LC Analysis of Bevacizumab for Intact Bioanalysis of Therapeutic Monoclonal Antibodies

モノクローナル抗体医薬品の完全なバイオアッセイのためのベバシズマブの高感度および高精度逆相LC分析

Author (5)： YAMADA Tomohiro (School of Pharmaceutical Sciences, University of Shizuoka) ,  MIZUNO Hajime (School of Pharmaceutical Sciences, University of Shizuoka) ,  Zhe MIN Jun (Key Laboratory for Natural Resource of Changbai Mountain & Functional Molecules, Ministry of Education, College of Pharmacy, Yanbian University) ,  TOYO'OKA Toshimasa (School of Pharmaceutical Sciences, University of Shizuoka) ,  TODOROKI Kenichiro (School of Pharmaceutical Sciences, University of Shizuoka)
Material： Chromatography  (Journal of Separation and Detection Sciences)
Volume： 39  Issue： 1  Page： 21-26(J-STAGE)  Publication year： 2018 
JST Material Number： L1501A  ISSN： 1342-8284  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *reversed-phase HPLC ,...
Semi thesaurus term： *Bevacizumab ,...

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Author keywords (4)： High-temperature reversed-phase LC ,  Bevacizumab ,  Therapeutic monoclonal antibody ,  Bioanalysis

JST classification (3)： Bioassay  (EA03060N) ,  Analysis of drugs  (GV01040Q) ,  Chromatography and electrophoretic analysis of organic compounds  (CC04034H)

Reference (27)：

• [1] Chan, A. C.; Carter, P. J. Nat. Rev. Immunol. 2010, 10, 301-316.
• [2] Weiner, L. M.; Surana, R.; Wang, S. Nat. Rev. Immunol. 2010, 10, 317-327.
• [3] Sliwkowski, M. X.; Mellman, I. Science 2013, 341, 1192-1198.
• [4] Lobo, E. D.; Hansen, R. J.; Balthasar, J. P. J. Pharm. Sci. 2004, 93, 2645-2668.
• [5] Wang, W.; Wang, E. Q.; Balthasar, J. P. Clin. Pharmacol. Ther. 2008, 84, 548-558.

Terms in the title (7)： モノクローナル抗体 ,  医薬品 ,  バイオアッセイ ,  ベバシズマブ ,  高感度 ,  逆相LC ,  分析