Art

J-GLOBAL ID：201802236965619146   Reference number：18A1026831

Up-Regulation of PI 3-Kinases and the Activation of PI3K-Akt Signaling Pathway in Cancer Stem-Like Cells Through DNA Hypomethylation Mediated by the Cancer Microenvironment

癌微小環境により仲介されるDNA低メチル化を介した癌幹様細胞におけるPI3キナーゼのアップレギュレーションとPI3K-Aktシグナル伝達経路の活性化【JST・京大機械翻訳】

Author (17)： Oo Aung Ko Ko (Department of Medical Bioengineering, Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530, Japan) ,  Oo Aung Ko Ko (Department of Biotechnology, Mandalay Technological University, Mandalay, Myanmar) ,  Calle Anna Sanchez (Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, Tokyo 104-0045, Japan) ,  Nair Neha (Department of Medical Bioengineering, Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530, Japan) ,  Mahmud Hafizah (Department of Medical Bioengineering, Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530, Japan) ,  Vaidyanath Arun (Department of Medical Bioengineering, Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530, Japan) ,  Yamauchi Junya (Department of Medical Bioengineering, Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530, Japan) ,  Khayrani Aprilliana Cahya (Department of Medical Bioengineering, Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530, Japan) ,  Du Juan (Department of Medical Bioengineering, Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530, Japan) ,  Alam Md Jahangir (Department of Medical Bioengineering, Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530, Japan) ,  Seno Akimasa (Department of Medical Bioengineering, Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530, Japan) ,  Mizutani Akifumi (Department of Medical Bioengineering, Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530, Japan) ,  Murakami Hiroshi (Department of Medical Bioengineering, Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530, Japan) ,  Iwasaki Yoshiaki (Department of Gastroenterology and Hepatology, Graduate School of Medicine, Okayama University, Okayama 700-8558, Japan) ,  Chen Ling (Department of Pathology, Tianjin Central Hospital of Gynecology Obstetrics, Tianjin 300100, People’s Republic of China) ,  Kasai Tomonari (Department of Medical Bioengineering, Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530, Japan) ,  Seno Masaharu (Department of Medical Bioengineering, Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530, Japan)
Material： Translational Oncology
Volume： 11  Issue： 3  Page： 653-663  Publication year： 2018 
JST Material Number： W2898A  ISSN： 1936-5233  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Previously, we have succeeded ...

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Thesaurus term： phenotype ,  *methylation ,  differentiation(biology) ,  *up-regulation ,  in vitro experiment ,  adenocarcinoma ,  *DNA ,  gene ,  characterization ,  tumor
Semi thesaurus term： DNAメチル化 ,  悪性腫瘍 ,  自己再生 ,  *低メチル化 ,  *微小環境 , 【Automatic Indexing@JST】

JST classification (2)： Carcinogenic mechanisms and factors  (GE02020C) ,  Cell physiology in general  (EF02010S)

Terms in the title (13)： 癌 ,  微小環境 ,  仲介 ,  DNA ,  低メチル化 ,  幹 ,  細胞 ,  PI3キナーゼ ,  アップレギュレーション ,  PI3K ,  Akt ,  シグナル伝達経路 ,  活性化