Art

J-GLOBAL ID：201802241158094547   Reference number：18A1005247

Targeted proteomics reveals promising biomarkers of disease activity and organ involvement in antineutrophil cytoplasmic antibody-associated vasculitis

標的プロテオミクスは抗好中球細胞質抗体関連血管炎における疾患活性と器官関与の有望なバイオマーカーを明らかにする【JST・京大機械翻訳】

Author (15)： Ishizaki Jun (Department of Hematology, Clinical Immunology, and Infectious Diseases, Ehime University Graduate School of Medicine, Toon, Japan) ,  Takemori Ayako (Division of Proteomics Research, Proteo-Science Center, Ehime University, Toon, Japan) ,  Suemori Koichiro (Department of Hematology, Clinical Immunology, and Infectious Diseases, Ehime University Graduate School of Medicine, Toon, Japan) ,  Matsumoto Takuya (Department of Hematology, Clinical Immunology, and Infectious Diseases, Ehime University Graduate School of Medicine, Toon, Japan) ,  Akita Yoko (Department of Hematology, Clinical Immunology, and Infectious Diseases, Ehime University Graduate School of Medicine, Toon, Japan) ,  Sada Ken-ei (Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan) ,  Yuzawa Yukio (Department of Nephrology, Fujita Health University School of Medicine, Aichi, Japan) ,  Amano Koichi (Department of Rheumatology and Clinical Immunology, Saitama Medical Center, Saitama Medical University, Saitama, Japan) ,  Takasaki Yoshinari (Department of Rheumatology, Juntendo University Koshigaya Hospital, Saitama, Japan) ,  Harigai Masayoshi (Division of Epidemiology and Pharmacoepidemiology of Rheumatic Diseases, Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan) ,  Arimura Yoshihiro (Nephrology and Rheumatology, First Department of Internal Medicine, Kyorin University School of Medicine, Tokyo, Japan) ,  Makino Hirofumi (Okayama University Hospital, Okayama, Japan) ,  Yasukawa Masaki (Department of Hematology, Clinical Immunology, and Infectious Diseases, Ehime University Graduate School of Medicine, Toon, Japan) ,  Takemori Nobuaki (Division of Proteomics Research, Proteo-Science Center, Ehime University, Toon, Japan) ,  Hasegawa Hitoshi (Department of Hematology, Clinical Immunology, and Infectious Diseases, Ehime University Graduate School of Medicine, Toon, Japan)
Material： Arthritis Research & Therapy (Web)
Volume： 19  Issue： 1  Page： 218  Publication year： 2017 
JST Material Number： U7412A  ISSN： 1478-6362  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Background Targeted proteomics...

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Thesaurus term： remission ,  serum concentration ,  mass spectrometry ,  Serum ,  infectious disease ,  *biomarker ,  myeloperoxidase ,  metalloproteinase ,  *proteomics ,  quantitative analysis (analytical chemistry) ,  targeting ,  patient ,  therapy ,  glycoprotein ,  Tissue Inhibitor of Metalloproteinase-1 ,  peroxidase

Author keywords (6)： Antineutrophil cytoplasmic antibody-associated vasculitis ,  Biomarkers ,  Targeted proteomics ,  Microscopic polyangiitis ,  Granulomatosis with polyangiitis ,  Eosinophilic granulomatosis with polyangiitis

JST classification (4)： Proteins and peptides in general  (EB03010N) ,  Miscellaneous analytical methods of organic compounds  (CC08034J) ,  Biochemical analytical methods  (EA03030G) ,  Blood tests(=hematologic tests)  (GC02050D)

Reference (59)：

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• Kidney Dis (Basel); Overview of the pathogenesis of ANCA-associated vasculitis; H Xiao, P Hu, RJ Falk, JC Jennette; 1; 4; 2016; 205-15; 10.1159/000442323; CR2;
• Curr Opin Rheumatol; Controversies in small vessel vasculitis - comparing the rheumatology and nephrology views; RJ Falk, GS Hoffman; 19; 1; 2007; 1-9; CR3;
• Arthritis Rheum; Prediction of relapses in Wegener’s granulomatosis by measurement of antineutrophil cytoplasmic antibody levels: a prospective study; MM Boomsma, CA Stegeman, MJ Leij, W Oost, J Hermans, CG Kallenberg; 43; 9; 2000; 2025-33; 10.1002/1529-0131(200009)43:9<2025::AID-ANR13>3.0.CO;2-O; CR4;
• Rheumatology (Oxford); Are antineutrophil cytoplasmic antibodies a marker predictive of relapse in Wegener’s granulomatosis? A prospective study; T Girard, A Mahr, LH Noël, JF Cordier, P Lesavre, MH André; 40; 2; 2001; 147-51; 10.1093/rheumatology/40.2.147; CR5;

Terms in the title (7)： 標的 ,  プロテオミクス ,  抗好中球細胞質抗体関連血管炎 ,  疾患 ,  活性 ,  器官 ,  バイオマーカー