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J-GLOBAL ID：201802242120083191   Reference number：18A0570578

Time-dependent distinct roles of Toll-like receptor 4 in a house dust mite-induced asthma mouse model

ハウスダストダニ誘発ぜん息マウスモデルにおけるToll様受容体4の時間依存の異なる役割【Powered by NICT】

Author (9)： Ishii T. (Department of Pharmacotherapy, Research Institute of Pharmaceutical Sciences, Musashino University, Tokyo, Japan) ,  Ishii T. (Department of Pulmonary Medicine, Faculty of Medicine, University of Tokyo, Tokyo, Japan) ,  Niikura Y. (Department of Pharmacotherapy, Research Institute of Pharmaceutical Sciences, Musashino University, Tokyo, Japan) ,  Kurata K. (ITEA Inc., Institute of Tokyo Environmental Allergy, Tokyo, Japan) ,  Muroi M. (Research Institute of Pharmaceutical Sciences, Musashino University, Tokyo, Japan) ,  Tanamoto K. (Research Institute of Pharmaceutical Sciences, Musashino University, Tokyo, Japan) ,  Nagase T. (Department of Pulmonary Medicine, Faculty of Medicine, University of Tokyo, Tokyo, Japan) ,  Sakaguchi M. (Department of Veterinary Microbiology, School of Veterinary Medicine, Azabu University, Kanagawa, Japan) ,  Yamashita N. (Department of Pharmacotherapy, Research Institute of Pharmaceutical Sciences, Musashino University, Tokyo, Japan)
Material： Scandinavian Journal of Immunology  (Scand J Immunol)
Volume： 87  Issue： 3  Page： ROMBUNNO.12641  Publication year： 2018 
JST Material Number： C0650B  ISSN： 0300-9475  CODEN： SJIMAX  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： House dust mites (HDMs) are a ...

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Thesaurus term： Inflammation ,  *asthma ,  natural immunity ,  knockout mouse ,  Neutrophils ,  human ,  allergen ,  immunoglobulin E ,  lipopolysaccharide ,  sensitization (immunology) ,  Eosinophils ,  intranasal administration ,  *Toll-Like Receptor 4 ,  *mouse model ,  laboratory animal ,  Mus musculus
Semi thesaurus term： 好酸球浸潤 , 【Automatic Indexing@JST】

Author keywords (5)： asthma ,  eosinophils ,  experimental animal ,  inflammation ,  lipopolysaccharide

JST classification (3)： Cell physiology in general  (EF02010S) ,  Receptors on cell membrane  (EF04030C) ,  Biological function  (EB06020T)

Terms in the title (6)： 誘発 ,  ぜん息 ,  マウスモデル ,  Toll様受容体4 ,  時間依存 ,  役割