Art

J-GLOBAL ID：201802245489967377   Reference number：18A1913633

Life-threatening Hyperkalemia Associated with Axitinib Treatment in Patients with Recurrent Renal Carcinoma

再発性腎癌患者におけるアキシチニブ治療に関連した致命的高カリウム血症

Author (13)： Godo Shigeo (Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Japan) ,  Godo Shigeo (Department of Emergency and Critical Care Medicine, Tohoku University Hospital, Japan) ,  Yoshida Yoshitaro (Department of Emergency and Critical Care Medicine, Tohoku University Hospital, Japan) ,  Kawamorita Naoki (Department of Urology, Tohoku University Graduate School of Medicine, Japan) ,  Mitsuzuka Koji (Department of Urology, Tohoku University Graduate School of Medicine, Japan) ,  Kawazoe Yu (Department of Emergency and Critical Care Medicine, Tohoku University Hospital, Japan) ,  Fujita Motoo (Department of Emergency and Critical Care Medicine, Tohoku University Hospital, Japan) ,  Kudo Daisuke (Department of Emergency and Critical Care Medicine, Tohoku University Hospital, Japan) ,  Kudo Daisuke (Division of Emergency and Critical Care Medicine, Tohoku University Graduate School of Medicine, Japan) ,  Nomura Ryosuke (Department of Emergency and Critical Care Medicine, Tohoku University Hospital, Japan) ,  Shimokawa Hiroaki (Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Japan) ,  Kushimoto Shigeki (Department of Emergency and Critical Care Medicine, Tohoku University Hospital, Japan) ,  Kushimoto Shigeki (Division of Emergency and Critical Care Medicine, Tohoku University Graduate School of Medicine, Japan)
Material： Internal Medicine (Web)  (Intern Med (Web))
Volume： 57  Issue： 19  Page： 2895-2900(J-STAGE)  Publication year： 2018 
JST Material Number： U0033A  ISSN： 1349-7235  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： *Advanced renal cell carcinoma

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Author keywords (4)： adverse event ,  axitinib ,  hyperkalemia ,  renal cell carcinoma

JST classification (3)： Clinical oncology in general  (GE03010Y) ,  Urogenital tumors(=neoplasms)  (GM04000S) ,  Clinical application of antitumor(=antineoplastic)drugs  (GW16020L)

Substance index (1)： Axitinib

Reference (29)：

• 1. Escudier B, Gore M. Axitinib for the management of metastatic renal cell carcinoma. Drugs R D 11: 113-126, 2011.
• 2. Keefe DM, Bateman EH. Tumor control versus adverse events with targeted anticancer therapies. Nat Rev Clin Oncol 9: 98-109, 2011.
• 3. Borst DL, Arruda LS, MacLean E, Pithavala YK, Morgado JE. Common questions regarding clinical use of axitinib in advanced renal cell carcinoma. Am J Health Syst Pharm 71: 1092-1096, 2014.
• 4. Matias M, Le Teuff G, Albiges L, et al. Real world prospective experience of axitinib in metastatic renal cell carcinoma in a large comprehensive cancer centre. Eur J Cancer 79: 185-192, 2017.
• 5. Brufau BP, Cerqueda CS, Villalba LB, Izquierdo RS, Gonzalez BM, Molina CN. Metastatic renal cell carcinoma: radiologic findings and assessment of response to targeted antiangiogenic therapy by using multidetector CT. Radiographics 33: 1691-1716, 2013.

Terms in the title (6)： 再発 ,  腎癌 ,  患者 ,  アキシチニブ ,  治療 ,  高カリウム血症