Art

J-GLOBAL ID：201802245790499044   Reference number：18A2209210

Surface microstructures are associated with mutational intratumoral heterogeneity in colorectal tumors

表面微細構造は大腸癌における変異腫瘍内不均一性と関連する

Author (23)： HARADA Taku (Sapporo Medical Univ. School of Medicine, Sapporo, JPN) ,  HARADA Taku (Teine-Keijinkai Hospital, Sapporo, JPN) ,  YAMAMOTO Eiichiro (Sapporo Medical Univ. School of Medicine, Sapporo, JPN) ,  YAMANO Hiro-o (Sapporo Medical Univ. School of Medicine, Sapporo, JPN) ,  AOKI Hironori (Sapporo Medical Univ. School of Medicine, Sapporo, JPN) ,  AOKI Hironori (Teine-Keijinkai Hospital, Sapporo, JPN) ,  MATSUSHITA Hiro-o (Akita Red Cross Hospital, Akita, JPN) ,  YOSHIKAWA Kenjiro (Akita Red Cross Hospital, Akita, JPN) ,  TAKAGI Ryo (Akita Red Cross Hospital, Akita, JPN) ,  HARADA Eiji (Akita Red Cross Hospital, Akita, JPN) ,  TANAKA Yoshihito (Akita Red Cross Hospital, Akita, JPN) ,  YOSHIDA Yuko (Akita Red Cross Hospital, Akita, JPN) ,  EIZUKA Makoto (Iwate Medical Univ., Morioka, JPN) ,  YOROZU Akira (Sapporo Medical Univ. School of Medicine, Sapporo, JPN) ,  SUDO Gota (Sapporo Medical Univ. School of Medicine, Sapporo, JPN) ,  KITAJIMA Hiroshi (Sapporo Medical Univ. School of Medicine, Sapporo, JPN) ,  NIINUMA Takeshi (Sapporo Medical Univ. School of Medicine, Sapporo, JPN) ,  KAI Masahiro (Sapporo Medical Univ. School of Medicine, Sapporo, JPN) ,  SASAKI Yasushi (Sapporo Medical Univ. School of Medicine, Sapporo, JPN) ,  TOKINO Takashi (Sapporo Medical Univ. School of Medicine, Sapporo, JPN) ,  SUGAI Tamotsu (Iwate Medical Univ., Morioka, JPN) ,  NAKASE Hiroshi (Sapporo Medical Univ. School of Medicine, Sapporo, JPN) ,  SUZUKI Hiromu (Sapporo Medical Univ. School of Medicine, Sapporo, JPN)
Material： Journal of Gastroenterology  (J Gastroenterol)
Volume： 53  Issue： 12  Page： 1241-1252  Publication year： 2018 
JST Material Number： Z0748A  ISSN： 0944-1174  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： genetic variation ,...

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JST classification (2)： Tumors(=neoplasms)of digestive system  (GH04000D) ,  Clinical oncology in general  (GE03010Y)

Reference (38)：

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• Jones S, Chen WD, Parmigiani G, et al. Comparative lesion sequencing provides insights into tumor evolution. Proc Natl Acad Sci USA. 2008;105:4283-8.
• Smith G, Carey FA, Beattie J, et al. Mutations in APC, Kirsten-ras, and p53-alternative genetic pathways to colorectal cancer. Proc Natl Acad Sci USA. 2002;99:9433-8.
• Sottoriva A, Kang H, Ma Z, et al. A Big Bang model of human colorectal tumor growth. Nat Genet. 2015;47:209-16.
• Kim TM, Jung SH, An CH, et al. Subclonal genomic architectures of primary and metastatic colorectal cancer based on intratumoral genetic heterogeneity. Clin Cancer Res. 2015;21:4461-72.

Terms in the title (4)： 表面微細構造 ,  大腸癌 ,  変異 ,  腫瘍内不均一性