Art

J-GLOBAL ID：201802246126575805   Reference number：18A1289854

Identification of Mepenzolate Derivatives With Long-Acting Bronchodilatory Activity

長時間作用性気管支拡張活性を有するメペンゾラート誘導体の同定【JST・京大機械翻訳】

Author (10)： Tanaka Ken-Ichiro (Research Institute of Pharmaceutical Sciences, Faculty of Pharmacy, Musashino University) ,  Yamakawa Naoki (School of Pharmacy, Shujitsu University) ,  Yamashita Yasunobu (Molecular Profiling Research Center for Drug Discovery, National Institute of Advanced Industrial Science and Technology) ,  Asano Teita (Institute of Medical Science, School of Medicine, St. Marianna University) ,  Kanda Yuki (Research Institute of Pharmaceutical Sciences, Faculty of Pharmacy, Musashino University) ,  Takafuji Ayaka (Research Institute of Pharmaceutical Sciences, Faculty of Pharmacy, Musashino University) ,  Kawahara Masahiro (Research Institute of Pharmaceutical Sciences, Faculty of Pharmacy, Musashino University) ,  Takenaga Mitsuko (Institute of Medical Science, School of Medicine, St. Marianna University) ,  Fukunishi Yoshifumi (Molecular Profiling Research Center for Drug Discovery, National Institute of Advanced Industrial Science and Technology) ,  Mizushima Tohru (LTT Bio-Pharma Co., Ltd.)
Material： Frontiers in Pharmacology (Web)
Volume： 9  Page： 344  Publication year： 2018 
JST Material Number： U7091A  ISSN： 1663-9812  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： The standard treatment for chr...

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Thesaurus term： Pulmonary Emphysema ,  anti-inflammatory action ,  bronchodilator ,  *Bronchiectasis ,  M3 receptor ,  antiphlogistic ,  Structure-Activity Relationship ,  bromide ,  chronic obstructive pulmonary disease ,  affinity ,  elastase ,  mouse model
Semi thesaurus term： 持続性 ,  アンタゴニスト , 【Automatic Indexing@JST】

Author keywords (4)： chronic obstructive pulmonary disease ,  anti-inflammatory ,  long-acting bronchodilatory activity ,  mepenzolate

JST classification (2)： Drug therapy(=pharmacotherapy)for respiratory system diseases  (GI05020J) ,  Basic research of drugs acting on respiration and respiratory system  (GW08010J)

Substance index (1)： Mepenzolate

Terms in the title (5)： 気管支拡張 ,  活性 ,  メペンゾラート ,  誘導体 ,  同定