Art

J-GLOBAL ID：201802246251383133   Reference number：18A1689956

Tbx6 Induces Nascent Mesoderm from Pluripotent Stem Cells and Temporally Controls Cardiac versus Somite Lineage Diversification

Tbx6は多能性幹細胞からの新生児を誘導し,時間的に心臓対体節系統の多様化を制御する【JST・京大機械翻訳】

Author (27)： Sadahiro Taketaro (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Isomi Mari (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Muraoka Naoto (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Muraoka Naoto (Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Kojima Hidenori (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Haginiwa Sho (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Kurotsu Shota (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Tamura Fumiya (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Tani Hidenori (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Tohyama Shugo (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Fujita Jun (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Miyoshi Hiroyuki (Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Kawamura Yoshifumi (Japan Biological Informatics Consortium (JBiC), Koto-ku, Tokyo 135-8073, Japan) ,  Goshima Naoki (Molecular Profiling Research Center for Drug Discovery, National Institute of Advanced Industrial Science and Technology, Koto-ku, Tokyo 135-0064, Japan) ,  Iwasaki Yuka W. (Department of Molecular Biology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Murano Kensaku (Department of Molecular Biology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Saito Kuniaki (Department of Molecular Biology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Saito Kuniaki (Invertebrate Genetics Laboratory, National Institute of Genetics, Research Organization of Information and Systems (ROIS), Mishima, Shizuoka 411-8540, Japan) ,  Saito Kuniaki (Department of Genetics, The Graduate University for Advanced Studies (SOKENDAI), Hayama, Kanagawa 240-0193, Japan) ,  Oda Mayumi (Department of Systems Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Andersen Peter (Division of Cardiology, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA) ,  Kwon Chulan (Division of Cardiology, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA) ,  Uosaki Hideki (Division of Cardiology, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA) ,  Uosaki Hideki (Division of Regenerative Medicine, Center for Molecular Medicine, Jichi Medical University, Shimotsuke, Tochigi 329-0498, Japan) ,  Nishizono Hirofumi (Life Science Research Center, University of Toyama, Sugitani, Toyama 930-0194, Japan) ,  Fukuda Keiichi (Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Ieda Masaki (Department of Cardiology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba City, Ibaraki 305-8575, Japan)
Material： Cell Stem Cell
Volume： 23  Issue： 3  Page： 382-395.e5  Publication year： 2018 
JST Material Number： W3106A  ISSN： 1934-5909  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： The mesoderm arises from pluri...

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Thesaurus term： human ,  Up-Regulation ,  *diversification ,  *versatility ,  *Heart ,  *pluripotent stem cell ,  *neonate ,  mesoderm ,  skeletal muscle ,  differentiation (biology) ,  chondrocyte ,  Sox2 ,  molecular mechanism ,  epiblast ,  *Tbx6

Author keywords (6)： mesoderm ,  Tbx6 ,  skeletal muscle ,  cardiovascular ,  chondrocyte ,  pluripotent stem cell

JST classification (1)： Development(=generation)and differentiation  (EJ16020W)

Terms in the title (8)： Tbx6 ,  多能性幹細胞 ,  新生児 ,  誘導 ,  心臓 ,  体節 ,  系統 ,  多様化