Art

J-GLOBAL ID：201802247376705405   Reference number：18A2174290

FBXW7 modulates malignant potential and cisplatin-induced apoptosis in cholangiocarcinoma through NOTCH1 and MCL1

FBXW7はNOTCJ1及びMCL1を介して胆管癌において悪性度及びシスプラチン誘発性アポトーシスを調節する

Author (15)： Mori Akiko (Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Masuda Kunihiro (Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Ohtsuka Hideo (Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Shijo Masahiro (Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Ariake Kyohei (Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Fukase Koji (Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Sakata Naoaki (Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Mizuma Masamichi (Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Morikawa Takanori (Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Hayashi Hiroki (Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Nakagawa Kei (Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Motoi Fuyuhiko (Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Naitoh Takeshi (Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Fujishima Fumiyoshi (Department of Pathology, Tohoku University Hospital, Sendai, Japan) ,  Unno Michiaki (Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan)
Material： Cancer Science (Web)  (Cancer Sci (Web))
Volume： 109  Issue： 12  Page： 3883-3895  Publication year： 2018 
JST Material Number： U0505A  ISSN： 1349-7006  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： cisplatin ,...

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Author keywords (5)： cholangiocarcinoma ,  cisplatin ,  FBXW7 protein ,  myeloid cell leukemia sequence 1 protein ,  NOTCH1 protein

JST classification (2)： Tumors(=neoplasms)of digestive system  (GH04000D) ,  Clinical oncology in general  (GE03010Y)

Terms in the title (6)： FBXW7 ,  胆管癌 ,  悪性度 ,  シスプラチン ,  アポトーシス ,  調節