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J-GLOBAL ID：201802251380404539   Reference number：18A0817777

PET probe detecting non-small cell lung cancer susceptible to epidermal growth factor receptor tyrosine kinase inhibitor therapy

上皮成長因子受容体チロシンキナーゼ阻害剤療法に感受性の非小細胞肺癌を検出するPETプローブ【JST・京大機械翻訳】

Author (14)： Makino Akira (Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-Adachi-cho, Sakyo-ku, Kyoto 6068501, Japan) ,  Makino Akira (Biomedical Imaging Research Center (BIRC), University of Fukui, 23-3 Matsuoka-shimoaizuki, Eiheiji-cho, Yoshida-gun, Fukui 9101193, Japan) ,  Miyazaki Anna (Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-Adachi-cho, Sakyo-ku, Kyoto 6068501, Japan) ,  Tomoike Ayaka (Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-Adachi-cho, Sakyo-ku, Kyoto 6068501, Japan) ,  Kimura Hiroyuki (Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-Adachi-cho, Sakyo-ku, Kyoto 6068501, Japan) ,  Kimura Hiroyuki (Department of Analytical and Bioinorganic Chemistry, Kyoto Pharmaceutical University, Kyoto 6078414, Japan) ,  Arimitsu Kenji (Department of Analytical and Bioinorganic Chemistry, Kyoto Pharmaceutical University, Kyoto 6078414, Japan) ,  Hirata Masahiko (Graduate School of Pharmaceutical Sciences, Osaka University of Pharmaceutical Sciences, Osaka 5691041, Japan) ,  Ohmomo Yoshiro (Graduate School of Pharmaceutical Sciences, Osaka University of Pharmaceutical Sciences, Osaka 5691041, Japan) ,  Nishii Ryuichi (National Institute of Radiological Sciences, Chiba 2638555, Japan) ,  Okazawa Hidehiko (Biomedical Imaging Research Center (BIRC), University of Fukui, 23-3 Matsuoka-shimoaizuki, Eiheiji-cho, Yoshida-gun, Fukui 9101193, Japan) ,  Kiyono Yasushi (Biomedical Imaging Research Center (BIRC), University of Fukui, 23-3 Matsuoka-shimoaizuki, Eiheiji-cho, Yoshida-gun, Fukui 9101193, Japan) ,  Ono Masahiro (Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-Adachi-cho, Sakyo-ku, Kyoto 6068501, Japan) ,  Saji Hideo (Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-Adachi-cho, Sakyo-ku, Kyoto 6068501, Japan)
Material： Bioorganic & Medicinal Chemistry  (Bioorganic and Medicinal Chemistry)
Volume： 26  Issue： 8  Page： 1609-1613  Publication year： 2018 
JST Material Number： W0556A  ISSN： 0968-0896  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Tyrosine kinase inhibitors for...

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Thesaurus term： *sensitivity ,  animal ,  molecular target therapy ,  visualization ,  PET (tomography) ,  image processing ,  affinity ,  *non-small cell lung cancer ,  Mutation ,  Drug Resistance ,  *EGF receptor ,  patient ,  *tyrosine kinase inhibitor ,  *EGFR-tyrosine kinase inhibitor ,  Genetic Variation
Semi thesaurus term： variation(biology) , 【Automatic Indexing@JST】

Author keywords (5)： Epidermal growth factor receptor ,  EGFR L858R and T790M mutations ,  Tyrosine kinase inhibitor ,  Positron emission tomography ,  In vivo imaging

JST classification (2)： Synthesis of drugs  (GV01030F) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Terms in the title (5)： 上皮成長因子受容体チロシンキナーゼ阻害剤 ,  療法 ,  感受性 ,  非小細胞肺癌 ,  PETプローブ