Art

J-GLOBAL ID：201802252426433786   Reference number：18A0975691

Augmented expression of cardiac ankyrin repeat protein is induced by pemetrexed and a possible marker for the pemetrexed resistance in mesothelioma cells

心臓アンキリン反復蛋白質の増加した発現は中皮腫細胞におけるペメトレキセドにより誘導され,ペメトレキセド耐性に対する可能なマーカーである【JST・京大機械翻訳】

Author (12)： Qin Yiyang (Division of Pathology and Cell Therapy, Chiba Cancer Center Research Institute, Chiba, Japan) ,  Qin Yiyang (Laboratory of Molecular Cell Biology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan) ,  Sekine Ikuo (Department of Medical Oncology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan) ,  Fan Mengmeng (Department of Medical Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan) ,  Takiguchi Yuichi (Department of Medical Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan) ,  Tada Yuji (Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan) ,  Shingyoji Masato (Division of Respirology, Chiba Cancer Center, Chiba, Japan) ,  Hanazono Michiko (Division of Pathology and Cell Therapy, Chiba Cancer Center Research Institute, Chiba, Japan) ,  Hanazono Michiko (Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan) ,  Yamaguchi Naoto (Laboratory of Molecular Cell Biology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan) ,  Tagawa Masatoshi (Division of Pathology and Cell Therapy, Chiba Cancer Center Research Institute, Chiba, Japan) ,  Tagawa Masatoshi (Department of Molecular Biology and Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan)
Material： Cancer Cell International (Web)
Volume： 17  Issue： 1  Page： 120  Publication year： 2017 
JST Material Number： U7315A  ISSN： 1475-2867  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Pemetrexed (PEM) is an anti-ca...

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Thesaurus term： DNA lesion ,  antitumor drug ,  DNA ,  RNA ,  *Mesothelioma ,  enzyme ,  Down-Regulation ,  biomarker ,  enzyme activity ,  Up-Regulation ,  Western blotting ,  p53 protein ,  DNA microarray ,  microarray ,  CARP ,  bioassay

Author keywords (4)： Mesothelioma ,  PEM resistance ,  Cardiac ankyrin repeat protein ,  Biomarker

JST classification (4)： Gene expression  (EC02040Q) ,  Biological function  (EB03040U) ,  Basic medicine on musculoskeletal system  (GG01020B) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Reference (23)：

• J Clin Oncol; Phase III study of PEM in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma; NJ Vogelzang, JJ Rusthoven, J Symanowski, C Denham, E Kaukel, P Ruffie; 21; 2003; 2636-2644; 10.1200/JCO.2003.11.136; citation_id=CR1
• Springerplus; An intrapleural administration of zoledronic acid for inoperable malignant mesothelioma patients: a phase I clinical study protocol; Y Tada, K Hiroshima, H Shimada, M Shingyoji, T Suzuki, H Umezawa; 5; 2016; 195; 10.1186/s40064-016-1893-2; citation_id=CR2
• Drug Des Dev Ther; Molecular mechanisms of cisplatin resistance in cervical cancer; H Zhu, H Luo, W Zhang, Z Shen, X Hu, X Zhu; 10; 2016; 1885-1889; 10.2147/DDDT.S106412; citation_id=CR3
• Cancer Metastasis Rev; Molecular basis of antifolate resistance; YG Assaraf; 26; 2007; 153-181; 10.1007/s10555-007-9049-z; citation_id=CR4
• Clin Cancer Res; Pharmacokinetic and pharmacodynamic evaluation of the glycinamide ribonucleotide formyltransferase inhibitor AG2034; HL McLeod, J Cassidy, RH Powrie, DG Priest, MA Zorbas, TW Synold; 6; 2000; 2677-2684; citation_id=CR5

Terms in the title (10)： 心臓 ,  アンキリン反復 ,  蛋白質 ,  発現 ,  中皮腫 ,  細胞 ,  ペメトレキセド ,  誘導 ,  耐性 ,  マーカー