Art

J-GLOBAL ID：201802253961445321   Reference number：18A2082535

T-type Calcium Channels Determine the Vulnerability of Dopaminergic Neurons to Mitochondrial Stress in Familial Parkinson Disease

家族性パーキンソン病におけるミトコンドリアストレスに対するドーパミン作動性ニューロンの脆弱性を決定するT型カルシウムチャンネル【JST・京大機械翻訳】

Author (15)： Tabata Yoshikuni (Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Tabata Yoshikuni (Tsukuba Research Laboratories, Eisai Co., Ltd, 5-1-3 Tokodai, Tsukuba-shi, Ibaraki 300-2635, Japan) ,  Imaizumi Yoichi (Tsukuba Research Laboratories, Eisai Co., Ltd, 5-1-3 Tokodai, Tsukuba-shi, Ibaraki 300-2635, Japan) ,  Sugawara Michiko (Tsukuba Research Laboratories, Eisai Co., Ltd, 5-1-3 Tokodai, Tsukuba-shi, Ibaraki 300-2635, Japan) ,  Andoh-Noda Tomoko (Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Banno Satoe (Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Chai MuhChyi (Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Sone Takefumi (Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Yamazaki Kazuto (Tsukuba Research Laboratories, Eisai Co., Ltd, 5-1-3 Tokodai, Tsukuba-shi, Ibaraki 300-2635, Japan) ,  Ito Masashi (Tsukuba Research Laboratories, Eisai Co., Ltd, 5-1-3 Tokodai, Tsukuba-shi, Ibaraki 300-2635, Japan) ,  Tsukahara Kappei (Tsukuba Research Laboratories, Eisai Co., Ltd, 5-1-3 Tokodai, Tsukuba-shi, Ibaraki 300-2635, Japan) ,  Saya Hideyuki (Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Hattori Nobutaka (Department of Neurology, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan) ,  Kohyama Jun (Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan) ,  Okano Hideyuki (Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan)
Material： Stem Cell Reports
Volume： 11  Issue： 5  Page： 1171-1184  Publication year： 2018 
JST Material Number： W3132A  ISSN： 2213-6711  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Parkinson disease (PD) is a pr...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=18A2082535&from=J-GLOBAL&jstjournalNo=W3132A") }}

Thesaurus term： substantia nigra ,  model ,  *neuron ,  screening(inspection) ,  Parkinson's disease ,  *mitochondria ,  sensitivity ,  phenotype ,  pathogenesis ,  apoptosis ,  patient
Semi thesaurus term： カルシウムホメオスタシス ,  アンタゴニスト ,  *脆弱性 ,  *ドーパミン作動性ニューロン , 【Automatic Indexing@JST】

Author keywords (5)： Parkinson disease ,  PARK2 ,  induced pluripotent stem cells ,  disease modeling ,  T-type calcium channels

JST classification (2)： Central nervous system  (EJ12030F) ,  Cell physiology in general  (EF02010S)

Terms in the title (6)： 家族性パーキンソン病 ,  ミトコンドリア ,  ストレス ,  ドーパミン作動性ニューロン ,  脆弱性 ,  T型カルシウムチャンネル