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J-GLOBAL ID：201802260332427818   Reference number：18A0430095

The Japanese Angelica acutiloba root and yokukansan increase hippocampal acetylcholine level, prevent apoptosis and improve memory in a rat model of repeated cerebral ischemia

日本Angelica acutiloba根と抑肝散は海馬アセチルコリンレベルを増加させ,アポトーシスを阻害して,繰り返し脳虚血のラットモデルにおける記憶を改善する【Powered by NICT】

Author (14)： Nogami-Hara Ai (Department of Neuropharmacology, Faculty of Pharmaceutical Science, Japan) ,  Nagao Masaki (A.I.G. Collaborative Research Institute for Aging and Brain Sciences, Japan) ,  Takasaki Kotaro (Department of Neuropharmacology, Faculty of Pharmaceutical Science, Japan) ,  Egashira Nobuaki (Department of Pharmacy, Kyushu University Hospital, Fukuoka 812-8582, Japan) ,  Fujikawa Risako (Department of Neuropharmacology, Faculty of Pharmaceutical Science, Japan) ,  Kubota Kaori (Department of Neuropharmacology, Faculty of Pharmaceutical Science, Japan) ,  Kubota Kaori (A.I.G. Collaborative Research Institute for Aging and Brain Sciences, Japan) ,  Watanabe Takuya (Department of Neuropharmacology, Faculty of Pharmaceutical Science, Japan) ,  Watanabe Takuya (A.I.G. Collaborative Research Institute for Aging and Brain Sciences, Japan) ,  Katsurabayashi Shutaro (Department of Neuropharmacology, Faculty of Pharmaceutical Science, Japan) ,  Hatip Funda Bolukbasi (Department of Medical Pharmacology, Faculty of Medicine, Pamukkale University, Denizli 22070, Turkey) ,  Hatip-Al-Khatib Izzettin (Department of Medical Pharmacology, Faculty of Medicine, Pamukkale University, Denizli 22070, Turkey) ,  Iwasaki Katsunori (Department of Neuropharmacology, Faculty of Pharmaceutical Science, Japan) ,  Iwasaki Katsunori (A.I.G. Collaborative Research Institute for Aging and Brain Sciences, Japan)
Material： Journal of Ethnopharmacology  (J Ethnopharmacol)
Volume： 214  Page： 190-196  Publication year： 2018 
JST Material Number： T0042A  ISSN： 0378-8741  CODEN： JETHDA  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Japanese Angelica acutiloba ro...

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Thesaurus term： memory disorder ,  safety ,  *Angelica acutiloba ,  *apoptosis ,  oral administration ,  *hippocampus ,  *Japan ,  *ischemia ,  *cerebral ischemia ,  high performance liquid chromatography ,  vascular dementia ,  *Angelica ,  Chinese drug
Semi thesaurus term： 神経細胞保護作用 ,  *抑肝散 , 【Automatic Indexing@JST】

Author keywords (5)： Acetylcholine ,  Apoptosis ,  Japanese Angelica root ,  Memory ,  Yokukansan

JST classification (1)： Basic research of pharmacology of crude drugs  (GX06020J)

Terms in the title (11)： 日本 ,  Angelica ,  根 ,  抑肝散 ,  海馬 ,  アセチルコリン ,  アポトーシス ,  阻害 ,  脳虚血 ,  ラット ,  モデル