Art

J-GLOBAL ID：201802260639642915   Reference number：18A0134289

Oral aversion to dietary sugar, ethanol and glycerol correlates with alterations in specific hepatic metabolites in a mouse model of human citrin deficiency

食事での糖,エタノール及びグリセロールへの経口嫌悪はヒトシトリン欠損症のマウスモデルにおける特異的な肝代謝物の変化と相関する【Powered by NICT】

Author (21)： Saheki Takeyori (Laboratory of Yamamura Project, Institute of Resource Development and Analysis, Kumamoto University, Kumamoto 860-0811, Japan) ,  Saheki Takeyori (Institute for Health Sciences, Tokushima Bunri University, Tokushima 770-8514, Japan) ,  Saheki Takeyori (Department of Molecular Oncology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8544, Japan) ,  Inoue Kanako (Institute for Health Sciences, Tokushima Bunri University, Tokushima 770-8514, Japan) ,  Ono Hiromi (Institute for Health Sciences, Tokushima Bunri University, Tokushima 770-8514, Japan) ,  Fujimoto Yuki (Laboratory of Yamamura Project, Institute of Resource Development and Analysis, Kumamoto University, Kumamoto 860-0811, Japan) ,  Furuie Sumie (Laboratory of Yamamura Project, Institute of Resource Development and Analysis, Kumamoto University, Kumamoto 860-0811, Japan) ,  Yamamura Ken-ichi (Laboratory of Yamamura Project, Institute of Resource Development and Analysis, Kumamoto University, Kumamoto 860-0811, Japan) ,  Kuroda Eishi (Department of Psychosomatic Internal Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8520, Japan) ,  Kuroda Eishi (Department of Molecular Oncology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8544, Japan) ,  Ushikai Miharu (Department of Psychosomatic Internal Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8520, Japan) ,  Ushikai Miharu (Department of Hygiene and Health Promotion Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8520, Japan) ,  Asakawa Akihiro (Department of Psychosomatic Internal Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8520, Japan) ,  Inui Akio (Department of Psychosomatic Internal Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8520, Japan) ,  Eto Kazuhiro (Department of Internal Medicine, Teikyo University, Tokyo 173-8605, Japan) ,  Kadowaki Takashi (Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan) ,  Moriyama Mitsuaki (Laboratory of Integrative Physiology in Veterinary Sciences, Osaka Prefecture University, Izumisano 598-8531, Japan) ,  Sinasac David S. (Alberta Children’s Hospital Research Institute, Department of Medical Genetics, Cumming School of Medicine, University of Calgary, Alberta T2N 2N1, Canada) ,  Yamamoto Takashi (Faculty of Health Science, Kio University, Koryo 635-0832, Japan) ,  Furukawa Tatsuhiko (Department of Molecular Oncology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8544, Japan) ,  Kobayashi Keiko (Department of Molecular Metabolism and Genetics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8544, Japan)
Material： Molecular Genetics and Metabolism  (Mol Genet Metab)
Volume： 120  Issue： 4  Page： 306-316  Publication year： 2017 
JST Material Number： E0820A  ISSN： 1096-7192  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Mice carrying simultaneous hom...

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Thesaurus term： phosphate ,  *model ,  gene ,  pathogenesis ,  wild type ,  mitochondria ,  *human(primates) ,  phenotype ,  phosphoric acid ,  protein ,  food ,  amino acid ,  aliphatic amine ,  aliphatic carboxylic acid ,  dicarboxylic acid ,  primary amine ,  aliphatic alcohol ,  polyol
Semi thesaurus term： *シトリン , 【Automatic Indexing@JST】

Author keywords (6)： Adult-onset type II citrullinemia (CTLN2) ,  ATP ,  Dietary aversion ,  Citrin deficiency ,  Glycerol 3-phosphate ,  Cytosolic NADH

JST classification (3)： Transport of cell membrane  (EF04020R) ,  Other senses  (EJ13040X) ,  Metabolic diseases,nutritional diseases in general.  (GD05010J)

Substance index (3)： Glutamic acid ,  Glycerol ,  Ethanol

Terms in the title (10)： 食事 ,  糖 ,  エタノール ,  グリセロール ,  嫌悪 ,  ヒト ,  シトリン欠損症 ,  マウスモデル ,  肝代謝 ,  相関