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J-GLOBAL ID：201802265342226646   Reference number：18A0522697

Inhibition of gingipains prevents Porphyromonas gingivalis-induced preterm birth and fetal death in pregnant mice

ギンギパインの阻害は妊娠マウスにおけるPorphyromonas gingivalis誘導早産および胎児死亡を予防する【Powered by NICT】

Author (6)： Takii Ryosuke (Department of Pharmacology, Graduate School of Dental Science, Kyushu University, Fukuoka 812-8582, Japan) ,  Takii Ryosuke (Department of Biochemistry and Molecular Biology, Yamaguchi University School of Medicine, Minami-Kogushi, Ube 755-8505, Japan) ,  Kadowaki Tomoko (Department of Pharmacology, Graduate School of Dental Science, Kyushu University, Fukuoka 812-8582, Japan) ,  Kadowaki Tomoko (Department of Frontier Life Science, Institute of Biomedical Sciences, Nagasaki University, Sakamoto 1-7-1, Nagasaki 852-8588, Japan) ,  Tsukuba Takayuki (Department of Dental Pharmacology, Institute of Biomedical Sciences, Nagasaki University, Sakamoto 1-7-1, Nagasaki 852-8588, Japan) ,  Yamamoto Kenji (Department of Pharmacology, Graduate School of Dental Science, Kyushu University, Fukuoka 812-8582, Japan)
Material： European Journal of Pharmacology  (Eur J Pharmacol)
Volume： 824  Page： 48-56  Publication year： 2018 
JST Material Number： B0841A  ISSN： 0014-2999  CODEN： EJPHAZ  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Accumulating epidemiological e...

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Thesaurus term： abortion ,  wild type ,  periodontal disease ,  placenta ,  *Porphyromonas ,  interferon gamma ,  *fetal death ,  epidemiology ,  infection ,  *fetus
Semi thesaurus term： 病原因子 ,  出生 ,  低出生体重 ,  *妊娠マウス ,  *ギンギパイン , 【Automatic Indexing@JST】

Author keywords (6)： Porphyromonas gingivalis ,  Preterm birth ,  Fetal death ,  Low birth weight ,  Gingipains ,  Gingipain inhibitors

JST classification (5)： Reproductive physiology in general  (EJ15010E) ,  Basic research of addictive analgesics and narcotics  (GW03080Z) ,  Basic research of histaminergic drugs and antihistaminergic drugs  (GW06010V) ,  Other hormones of verterbrates  (EB08070K) ,  Influence on plants  (EE05030G)

Terms in the title (8)： ギンギパイン ,  阻害 ,  妊娠マウス ,  Porphyromonas ,  誘導 ,  早産 ,  胎児死亡 ,  予防