Art

J-GLOBAL ID：201802266507155892   Reference number：18A1608046

Crystal structure of the ligand-free form of the Vps10 ectodomain of dimerized Sortilin at acidic pH

酸性pHにおける二量体化ソルチリンのVps10エクトドメインの配位子フリー型の結晶構造【JST・京大機械翻訳】

Author (4)： Yabe-Wada Toshiki (Department of Immunology, Kanazawa Medical University, Uchinada, Japan) ,  Matsuba Shintaro (Department of Immunology, Kanazawa Medical University, Uchinada, Japan) ,  Unno Masaki (Graduate School of Science and Engineering, Ibaraki University, Japan) ,  Onai Nobuyuki (Department of Immunology, Kanazawa Medical University, Uchinada, Japan)
Material： FEBS Letters  (for the Rapid Publication of Short Reports in Biochemistry, Biophysics)
Volume： 592  Issue： 15  Page： 2647-2657  Publication year： 2018 
JST Material Number： D0575A  ISSN： 0014-5793  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Sortilin is a multifunctional ...

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Thesaurus term： receptor ,  *dimerization ,  *crystal structure ,  flow cytometry ,  crystallization ,  interferon alpha ,  cytokine ,  conformational transition ,  hydrophobic interaction ,  secretion (physiology) ,  interface (surface) ,  *dimer ,  *domain structure ,  *sortilin ,  Genetic Variation
Semi thesaurus term： variation(biology) , 【Automatic Indexing@JST】

Author keywords (5)： cytokines ,  flow cytometry ,  innate immunity ,  protein trafficking ,  X-ray crystallography

JST classification (4)： Cell physiology in general  (EF02010S) ,  Biological function  (EB03040U) ,  Cytokines  (EB08090G) ,  Metabolic diseases,nutritional diseases in general.  (GD05010J)

Terms in the title (7)： 酸性 ,  pH ,  二量体化 ,  ソルチリン ,  エクトドメイン ,  配位子 ,  結晶構造