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J-GLOBAL ID：201802266517453925   Reference number：18A2242493

Unexpected high plasma xanthine oxidoreductase activity in female subjects with low levels of uric acid

低尿酸値の女性被験者における予想外に高い血漿中キサンチンオキシドレダクターゼ活性

Author (16)： Furuhashi Masato (Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan) ,  Mori Kazuma (Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan) ,  Tanaka Marenao (Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan) ,  Maeda Takuto (Department of Nephrology, Teine Keijinkai Hospital, Sapporo 006-8555, Japan) ,  Matsumoto Megumi (Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan) ,  Murase Takayo (Sanwa Kagaku Kenkyusho Co., Ltd., Inabe 511-0406, Japan) ,  Nakamura Takashi (Sanwa Kagaku Kenkyusho Co., Ltd., Inabe 511-0406, Japan) ,  Koyama Masayuki (Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan) ,  Koyama Masayuki (Department of Public Health, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan) ,  Moniwa Norihito (Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan) ,  Ohnishi Hirofumi (Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan) ,  Ohnishi Hirofumi (Department of Public Health, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan) ,  Saitoh Shigeyuki (Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan) ,  Saitoh Shigeyuki (Department of Nursing, Division of Medical and Behavioral Subjects, Sapporo Medical University School of Health Sciences, Sapporo 060-8543, Japan) ,  Shimamoto Kazuaki (Japan Health Care College, Sapporo 004-0839, Japan) ,  Miura Tetsuji (Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan)
Material： Endocrine Journal (Web)
Volume： 65  Issue： 11  Page： 1083-1092(J-STAGE)  Publication year： 2018 
JST Material Number： U1479A  ISSN： 1348-4540  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *xanthine oxidoreductase ,...

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Author keywords (5)： Xanthine oxidoreductase ,  Renal hypouricemia ,  Liver dysfunction ,  Insulin resistance ,  Exercise-induced acute kidney injury

JST classification (2)： Diagnostics of metabolic diseases,nutritional diseases.  (GD05020U) ,  Epidemiology  (GB03000E)

Substance index (3)： Xanthine ,  Hypoxanthine ,  Uric Acid

Reference (48)：

• 1 Wu XW, Lee CC, Muzny DM, Caskey CT (1989) Urate oxidase: primary structure and evolutionary implications. Proc Natl Acad Sci U S A 86: 9412-9416.
• 2 Matsuzawa Y, Funahashi T, Nakamura T (2011) The concept of metabolic syndrome: contribution of visceral fat accumulation and its molecular mechanism. J Atheroscler Thromb 18: 629-639.
• 3 Ohta T, Sakano T, Igarashi T, Itami N, Ogawa T, et al. (2004) Exercise-induced acute renal failure associated with renal hypouricaemia: results of a questionnaire-based survey in Japan. Nephrol Dial Transplant 19: 1447-1453.
• 4 Wakasugi M, Kazama JJ, Narita I, Konta T, Fujimoto S, et al. (2015) Association between hypouricemia and reduced kidney function: a cross-sectional population-based study in Japan. Am J Nephrol 41: 138-146.
• 5 Son CN, Kim JM, Kim SH, Cho SK, Choi CB, et al. (2016) Prevalence and possible causes of hypouricemia at a tertiary care hospital. Korean J Intern Med 31: 971-976.

Terms in the title (7)： 尿酸値 ,  女性 ,  被験者 ,  予想 ,  血漿 ,  キサンチンオキシドレダクターゼ ,  活性