Art

J-GLOBAL ID：201802266808059917   Reference number：18A2168581

Epirubicin-loaded polymeric micelles effectively treat axillary lymph nodes metastasis of breast cancer through selective accumulation and pH-triggered drug release

エピルビシン負荷高分子ミセルは選択的蓄積およびpH誘発薬物放出を介して乳癌の腋窩リンパ節転移を効果的に治療する

Author (9)： Chida Tsukasa (Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku, Yokohama, Kanagawa 226-8503, Japan) ,  Chida Tsukasa (Fuji Research Laboratories, Pharmaceutical Division, Kowa Co. Ltd., 332-1 Ohnoshinden, Fuji, Shizuoka, Japan) ,  Miura Yutaka (Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan) ,  Cabral Horacio (Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan) ,  Nomoto Takahiro (Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku, Yokohama, Kanagawa 226-8503, Japan) ,  Kataoka Kazunori (Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, Kawasaki 210-0821, Japan) ,  Kataoka Kazunori (Policy Alternatives Research Institute, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan) ,  Nishiyama Nobuhiro (Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku, Yokohama, Kanagawa 226-8503, Japan) ,  Nishiyama Nobuhiro (Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14, Tonomachi, Kawasaki-ku, Kawasaki 210-0821, Japan)
Material： Journal of Controlled Release  (J Control Release)
Volume： 292  Page： 130-140  Publication year： Dec. 28, 2018 
JST Material Number： C0308D  ISSN： 0168-3659  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *anthracycline antibiotics ,...
Semi thesaurus term： *エピルビシン負荷高分子ミセル ,...

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Author keywords (6)： Drug delivery ,  Polymeric micelle ,  pH-triggered drug release ,  Lymph node metastasis ,  Breast cancer ,  Epirubicin

JST classification (2)： Liquid preparations  (GY02020K) ,  Experimental treatment for tumors  (GE02040Y)

Substance index (1)： Epirubicin

Terms in the title (9)： エピルビシン ,  高分子ミセル ,  蓄積 ,  pH ,  誘発 ,  薬物放出 ,  乳癌 ,  腋窩リンパ節転移 ,  治療