Art

J-GLOBAL ID：201802267430391085   Reference number：18A0139413

The Dickkopf1-cytoskeleton-associated protein 4 axis creates a novel signalling pathway and may represent a molecular target for cancer therapy

Dickkopf1細胞骨格関連蛋白質-4軸は新規シグナル伝達経路を創造すると癌治療のための分子標的を示す可能性がある【Powered by NICT】

Author (3)： Kikuchi Akira (Department of Biochemistry and Molecular Biology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan) ,  Fumoto Katsumi (Department of Biochemistry and Molecular Biology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan) ,  Kimura Hirokazu (Department of Biochemistry and Molecular Biology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan)
Material： British Journal of Pharmacology  (Br J Pharmacol)
Volume： 174  Issue： 24  Page： 4651-4665  Publication year： 2017 
JST Material Number： B0334A  ISSN： 0007-1188  CODEN： BJPCB  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Dickkopf 1 (DKK1) is a secrete...

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Thesaurus term： endoplasmic reticulum ,  tumor cell ,  *cytoskeleton ,  tumorigenesis ,  tumor ,  secretory protein ,  membrane protein ,  lung tumor ,  LDL receptor ,  antibody ,  *protein
Semi thesaurus term： 創薬 ,  治療標的 ,  細胞表面 ,  Wnt蛋白質 , 【Automatic Indexing@JST】

JST classification (5)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Basic research of pharmacology of crude drugs  (GX06020J) ,  Receptors on cell membrane  (EF04030C) ,  Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W) ,  Bioactive peptides  (EB08100U)

Terms in the title (6)： 細胞骨格関連蛋白質 ,  シグナル伝達経路 ,  創造 ,  癌治療 ,  分子標的 ,  可能性