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J-GLOBAL ID：201802268954871869   Reference number：18A0551359

Supramolecular Complex of Methyl-β-cyclodextrin with Adamantane-Grafted Hyaluronic Acid as a Novel Antitumor Agent

新規抗腫瘍剤としてのアダマンタングラフトヒアルロン酸を用いたメチル-β-シクロデキストリンの超分子複合体

Author (6)： Elamin Khaled Mohamed (Department of Physical Pharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University) ,  Yamashita Yuki (Department of Physical Pharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University) ,  Higashi Taishi (Department of Physical Pharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University) ,  Motoyama Keiichi (Department of Physical Pharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University) ,  Arima Hidetoshi (Department of Physical Pharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University) ,  Arima Hidetoshi (Program for Leading Graduate Schools “HIGO (Health life science: Interdisciplinary and Glocal Oriented) Program,” Kumamoto University)
Material： Chemical and Pharmaceutical Bulletin (Web)
Volume： 66  Issue： 3  Page： 277-285(J-STAGE)  Publication year： 2018 
JST Material Number： U1401A  ISSN： 1347-5223  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *cyclodextrin ,...
Semi thesaurus term： HCT116 Cells ,...

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Author keywords (10)： methyl-β-cyclodextrin ,  hyaluronic acid ,  adamantane ,  supramolecular complex ,  antitumor agent ,  methyl-β-cyclodextrin ,  hyaluronic acid ,  adamantane ,  supramolecular complex ,  antitumor agent

JST classification (1)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Substance index (2)： Adamantane ,  DTAF

Reference (46)：

• 1) Lam J. K. W., Chow M. Y. T., Zhang Y., Leung S. W. S., Mol. Ther. Nucleic Acids, 4, e252 (2015).
• 2) Sliwkowski M. X., Mellman I., Science, 341, 1192-1198 (2013).
• 3) Bertrand N., Wu J., Xu X., Kamaly N., Farokhzad O. C., Adv. Drug Deliv. Rev., 66, 2-25 (2014).
• 4) Maeda H., Nakamura H., Fang J., Adv. Drug Deliv. Rev., 65, 71-79 (2013).
• 5) Xu X., Ho W., Zhang X., Bertrand N., Farokhzad O., Trends Mol. Med., 21, 223-232 (2015).

Terms in the title (6)： 抗腫瘍剤 ,  アダマンタン ,  グラフト ,  ヒアルロン酸 ,  メチル-β-シクロデキストリン ,  分子複合体