Rchr
J-GLOBAL ID:200901009681123305   Update date: May. 27, 2020

Arima Hidetoshi

アリマ ヒデトシ | Arima Hidetoshi
Affiliation and department:
Job title: Professor
Homepage URL  (1): http://seizai.pharm.kumamoto-u.ac.jp/index.html
Research field  (3): Pharmacology ,  Clinical pharmacy ,  Pharmaceuticals - analytical and physicochemistry
Research keywords  (2): Physical Pharmaceutics ,  Drug Delivery System
Research theme for competitive and other funds  (4):
  • 2001 - Delivery of Gene and Antitumor Drug by Cyclodextrin-containing Liposomes
  • 1999 - Protective effect of cyclodextrin derivatives on septic shock
  • 1998 - Effects of cyclodextrins on transporters and cytochrome P450
  • 1998 - Delivery of gene and siRNA by cyclodextrin/dendrimer conjugate
Papers (177):
MISC (62):
  • Yuki Kondo, Hiroko Tokumaru, Yoichi Ishitsuka, Tomoko Matsumoto, Makiko Taguchi, Keiichi Motoyama, Taishi Higashi, Hidetoshi Arima, Muneaki Matsuo, Katsumi Higaki, Kousaku Ohno, Tetsumi Irie. Corrigendum to “In vitro evaluation of 2-hydroxyalkylated β-cyclodextrins as potential therapeutic agents for Niemann-pick type C disease” (Molecular Genetics and Metabolism (2016) 118(3) (214-219) (S1096719216300579) (10.1016/j.ymgme.2016.04.014)). Molecular Genetics and Metabolism. 2017. 120. 296-297
  • Naoko Ohshita, Naoko Ohshita, Anna Tajima, Taishi Higashi, Keiichi Motoyama, Sawako Koyama, Ruriko Iibuchi, Shiuhei Mieda, Kenji Handa, Tomoaki Kimoto, Hidetoshi Arima, Hidetoshi Arima. Improvement of physicochemical stability of highly-concentrated antibodies using cyclodextrin polypseudorotaxane hydrogels. Asian Journal of Pharmaceutical Sciences. 2016. 11. 221-222
  • Yuki Maeda, Yuki Maeda, Keiichi Motoyama, Taishi Higashi, Yuka Horikoshi, Toru Takeo, Naomi Nakagata, Yuki Kurauchi, Hiroshi Katsuki, Yuki Kondo, Yoichi Ishitsuka, Tetsumi Irie, Tetsumi Irie, Takumi Era, Hidetoshi Arima, Hidetoshi Arima. Feasibility study of cyclodextrins as active pharmaceutical ingredients for the treatment of GM1-gangliosidosis. Asian Journal of Pharmaceutical Sciences. 2016. 11. 183-184
  • Keiichi Motoyama, Chiho Akao, Ryosuke Mitsuyasu, Taishi Higashi, Hidetoshi Arima, Hidetoshi Arima. Fucose-appended dendrimer/α-cyclodextrin conjugate as a novel NF-κB decoy carrier to Kupffer cells infulminant hepatitis mice induced by lipopolysaccharide. Asian Journal of Pharmaceutical Sciences. 2016. 11. 152-153
  • Mari Sugio, Tatsunori Hirotsu, Tatsunori Hirotsu, Taishi Higashi, Keiichi Motoyama, Fumitoshi Hirayama, Kaneto Uekama, Hidetoshi Arima, Hidetoshi Arima. Pharmaceutical properties of insulin conjugate with glucuronylglucosyl-β-cyclodextrin. Asian Journal of Pharmaceutical Sciences. 2016. 11. 120-121
more...
Patents (3):
  • Ointment Composition
  • Cyclodextrin-dendrimer conjugates as gene transfection vector.
  • Topical Formulation for Prostagrandin E1
Books (1):
  • Potential use of cyclodextrin/dendrimer conjugates as siRNA delivery carriers
    THE ICHIRO KANEHARA FOUNDATION 2012
Lectures and oral presentations  (66):
  • Design and Evaluation of shRNA Complex with Cyclodextrin/Dendrimer Conjugate for Treatment of Transthyretin Amyloidosis.
    (The 17th International Symposium on Amyloidosis 2018)
  • The Use of Cyclodextrins as Drug Delivery Carriers and Active Pharmaceutical Ingredients
    (9th Asian Cyclodextrin Conference (9ACC) 2017 2017)
  • Sustained and Controllable Release System of Insulin Utilizing the Combination Technology of Self-assembly PEGylation and Polypseudorotaxane Formation
    (9th Asian Cyclodextrin Conference (9ACC) 2017 2017)
  • Preparation and Evaluation of Folate PEG-appended Polyamidoamine Dendrimer (G3) Conjugates with Glucuronylglucosyl--cyclodextrin as Novel Tumor Cell-selective siRNA Carriers
    (9th Asian Cyclodextrin Conference (9ACC) 2017 2017)
  • Synergistic Adjuvant Effect of Combination of 2-Hydroxypropyl--Cyclodextrin and CpG-ODN
    (9th Asian Cyclodextrin Conference (9ACC) 2017 2017)
more...
Works (1):
  • Evaluation of Transdermal Immune System
    2003 - 2006
Education (3):
  • - 1991 Kumamoto University Graduate School, Division of Pharmaceutical Sciences
  • - 1986 Kumamoto University School of Pharmacy
  • - 1986 Kumamoto University Faculty of Pharmaceutical Science
Professional career (1):
  • Doctor of Philosophy (Pharmaceutical Science) (Kumamoto University)
Work history (6):
  • 2010 - Kumamoto University
  • 2010 - Professor,Faculty of Life Sciences(Pharmaceutical sciences group),Kumamoto University
  • 2007 - 2009 Professor,
  • 2003 - 2007 Associate Professor,
  • 2001 - 2003 Associate Professor,
Show all
Committee career (4):
  • 2001 - 2015 Cyclodextrin Sosiety, Japan Asia Oceanian Cyclodextrin League Chair(2015)
  • 2001 - 2015 Cyclodextrin Sosiety, Japan
  • 2001 - 2015 Cyclodextrin Sosiety, Japan
  • 2015 - Cyclodextrin Sosiety, Japan
Association Membership(s) (6):
American Association of Pharmaceutical Scicences ,  THE JAPANESE SOCIETY FOR THE STUDY OF XENOBIOTICS ,  THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  Asian Oceanian Cyclodextrin League Chair ,  Oligonucleotide Therapy Society
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