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J-GLOBAL ID：201802269856355852   Reference number：18A0339334

Overexpression of carboxylesterase contributes to the attenuation of cyanotoxin microcystin-LR toxicity

カルボキシルエステラーゼの過剰発現はシアン毒素-マイクロシスチン-LR毒性の減弱に寄与する【Powered by NICT】

Author (12)： Takumi Shota (Division of Food and Chemical Biology, Faculty of Fisheries, Kagoshima University, 890-0056 Kagoshima, Japan) ,  Takumi Shota (Department of Domestic Science, Kagoshima Women’s College, Kagoshima 890-8565, Japan) ,  Shimono Tai (Division of Food and Chemical Biology, Faculty of Fisheries, Kagoshima University, 890-0056 Kagoshima, Japan) ,  Ikema Satoshi (Division of Food and Chemical Biology, Faculty of Fisheries, Kagoshima University, 890-0056 Kagoshima, Japan) ,  Hotta Yuki (Division of Food and Chemical Biology, Faculty of Fisheries, Kagoshima University, 890-0056 Kagoshima, Japan) ,  Chigwechokha Petros K. (Division of Food and Chemical Biology, Faculty of Fisheries, Kagoshima University, 890-0056 Kagoshima, Japan) ,  Shiozaki Kazuhiro (Division of Food and Chemical Biology, Faculty of Fisheries, Kagoshima University, 890-0056 Kagoshima, Japan) ,  Sugiyama Yasumasa (Division of Food and Chemical Biology, Faculty of Fisheries, Kagoshima University, 890-0056 Kagoshima, Japan) ,  Hashimoto Mitsuru (College of Pharmaceutical Sciences, School of Clinical Pharmacy, Matsuyama University, 790-8578, Ehime, Japan) ,  Furukawa Tatsuhiko (Department of Molecular Oncology, Graduate School of Medical and Dental Sciences, Kagoshima University, 890-8544 Kagoshima, Japan) ,  Furukawa Tatsuhiko (Center for the Research of Advanced Diagnosis and Therapy of Cancer, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan) ,  Komatsu Masaharu (Division of Food and Chemical Biology, Faculty of Fisheries, Kagoshima University, 890-0056 Kagoshima, Japan)
Material： Comparative Biochemistry and Physiology. C. Toxicology & Pharmacology  (Comparative Biochemistry and Physiology. C. Pharmacology Toxicology & Endocrinology)
Volume： 194  Page： 22-27  Publication year： 2017 
JST Material Number： C0797A  ISSN： 1532-0456  CODEN： CBPCBB  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Microcystin-LR is a hepatotoxi...

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Thesaurus term： serine/threonine specific protein phosphatase ,  Cyanophyta ,  *toxicity ,  cytotoxicity ,  substrate(biochemistry) ,  *toxin ,  *carboxylesterase ,  interaction ,  *ester bond hydrolase
Semi thesaurus term： OATP1B3 ,  細胞株 ,  輸送体 ,  ミクロシスチン ,  *過剰発現 , 【Automatic Indexing@JST】

Author keywords (5)： Microcystin-LR ,  Carboxylesterase ,  Irinotecan ,  OATP1B3 ,  Overexpression

JST classification (1)： Influence on animals  (EE05040R)

Substance index (1)： PP1

Terms in the title (8)： カルボキシルエステラーゼ ,  過剰発現 ,  シアン ,  毒素 ,  シスチン ,  Lr ,  毒性 ,  減弱