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J-GLOBAL ID：201802271058141269   Reference number：18A1010907

Mansonone E from Mansonia gagei Inhibited α-MSH-Induced Melanogenesis in B16 Cells by Inhibiting CREB Expression and Phosphorylation in the PI3K/Akt Pathway

Mansonia gageiからのマンソノンEはCREB発現とPI3K/Akt経路におけるリン酸化の阻害によりB16細胞におけるα-MSH誘発性メラニン形成を阻害した

Author (9)： Nishina Atsuyoshi (College of Science and Technology, Nihon University) ,  Miura Airi (College of Science and Technology, Nihon University) ,  Goto Masaharu (College of Science and Technology, Nihon University) ,  Terakado Kahori (College of Science and Technology, Nihon University) ,  Sato Daisuke (Department of Biomedical Information Engineering, Graduate School of Medical Science, Yamagata University) ,  Kimura Hirokazu (School of Medical Technology, Faculty of Health Science, Gunma Paz University) ,  Hirai Yasuaki (Faculty of Arts and Sciences, Showa University) ,  Sato Hiroyasu (Rigaku Corporation) ,  Phay Nyunt (Botany Department, Pathein University)
Material： Biological and Pharmaceutical Bulletin (Web)
Volume： 41  Issue： 5  Page： 770-776(J-STAGE)  Publication year： 2018 
JST Material Number： U1402A  ISSN： 1347-5215  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Plants ,...
Semi thesaurus term： *cellular signal transduction ,...

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Author keywords (12)： Mansonia gagei ,  melanogenesis ,  B16 cell ,  mansonone E ,  cAMP response element binding protein (CREB) ,  Akt ,  Mansonia gagei ,  melanogenesis ,  B16 cell ,  mansonone E ,  cAMP response element binding protein (CREB) ,  Akt

JST classification (1)： Basic research of drugs acting on integumentum commune  (GW12010Y)

Substance index (1)： Mansonone E

Reference (35)：

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Terms in the title (11)： マンソノンE ,  CREB ,  発現 ,  PI3K ,  AKT ,  経路 ,  リン酸化 ,  阻害 ,  B16細胞 ,  α-MSH ,  メラニン形成