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J-GLOBAL ID：201802271659028656   Reference number：18A0695004

Structure-activity relationships of flavanones, flavanone glycosides, and flavones in anti-degranulation activity in rat basophilic leukemia RBL-2H3 cells

ラット好塩基球性白血病RBL-2H3細胞における抗脱顆粒活性におけるフラバノン,フラバノン配糖体,フラボンの構造活性相関

Author (6)： NOSHITA Toshiro (Prefectural Univ. Hiroshima, Hiroshima, JPN) ,  MIURA Kaori (Prefectural Univ. Hiroshima, Hiroshima, JPN) ,  IKEDA Kaoru (Prefectural Univ. Hiroshima, Hiroshima, JPN) ,  OUCHI Hidekazu (Kindai Univ., Higashiosaka, JPN) ,  MATSUMOTO Takuya (Prefectural Univ. Hiroshima, Hiroshima, JPN) ,  TAI Akihiro (Prefectural Univ. Hiroshima, Hiroshima, JPN)
Material： Journal of Natural Medicines  (J Nat Med)
Volume： 72  Issue： 2  Page： 551-556  Publication year： 2018 
JST Material Number： L5856A  ISSN： 1340-3443  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *tumor cell ,...
Semi thesaurus term： Type 1 allergy ,...

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JST classification (1)： Basic research of other drugs  (GW23010K)

Substance index (17)： Tectochrysin ,  Pilloin ,  Apigenin ,  Eriodictyol ,  Eriodictyol 7-O-glucoside ,  Eriocitrin ,  Quercetin ,  Chrysin ,  Diosmetin ,  Narirutin ,  Naringin ,  Naringenin ,  Neohesperidin ,  Pinocembrin ,  Luteolin ,  Hesperidin ,  Hesperetin

Reference (20)：

• Ferrer JL, Austin MB, Stewart C Jr, Noel JP (2008) Structure and function of enzymes involved in the biosynthesis of phenylpropanoids. Plant Physiol Biochem 46:356-370
• Havsteen BH (2002) The biochemistry and medical significance of the flavonoids. Pharmacol Ther 96:67-202
• Bae EA, Han MJ, Lee M, Kim DH (2000) In vitro inhibitory effect of some flavonoids on rotavirus infectivity. Biol Pharm Bull 23:1122-1124
• Gorinstein S, Leontowicz H, Leontowicz M, Krzeminski R, Gralak M, Jastrzebski Z, Park YS, Jung ST, Kang SG, Trakhtenberg S (2007) Effect of hesperidin and naringin on the plasma lipid profile and plasma antioxidant activity in rats fed a cholesterol-containing diet. J Sci Food Agric 87:1257-1262
• Yeh CC, Kao SJ, Lin CC, Wang SD, Liu CJ, Kao ST (2007) The immunomodulation of endotoxin-induced acute lung injury by hesperidin in vivo and in vitro. Life Sci 80:1821-1831

Terms in the title (9)： ラット ,  好塩基球性白血病 ,  RBL-2H3細胞 ,  脱顆粒 ,  活性 ,  フラバノン ,  配糖体 ,  フラボン ,  構造活性相関