Art

J-GLOBAL ID：201802279289517820   Reference number：18A0256591

Identification of highly sensitive biomarkers that can aid the early detection of pancreatic cancer using GC/MS/MS-based targeted metabolomics

GC/MS/MSベース標的メタボロミクスを用いたすい癌の早期発見を支援する高感度バイオマーカーの同定【Powered by NICT】

Author (28)： Hirata Yuichi (Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Hyogo, Japan) ,  Kobayashi Takashi (Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Hyogo, Japan) ,  Nishiumi Shin (Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Hyogo, Japan) ,  Yamanaka Kodai (Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Hyogo, Japan) ,  Nakagawa Takashi (Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Hyogo, Japan) ,  Fujigaki Seiji (Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Hyogo, Japan) ,  Iemoto Takao (Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Hyogo, Japan) ,  Kobayashi Makoto (Division of Chemotherapy and Clinical Research, National Cancer Center Research Institute, Tokyo, Japan) ,  Okusaka Takuji (Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital, Tokyo, Japan) ,  Nakamori Shoji (Departments of Hepato-Biliary-Pancreatic Surgery, Osaka National Hospital, National Hospital Organization, Osaka, Japan) ,  Shimahara Masashi (Department of Oral Surgery, Osaka Medical College, Osaka, Japan) ,  Ueno Takaaki (Department of Oral Surgery, Osaka Medical College, Osaka, Japan) ,  Tsuchida Akihiko (Department of Gastrointestinal and Pediatric Surgery, Tokyo Medical University, Tokyo, Japan) ,  Sata Naohiro (Department of Surgery, Jichi Medical University, Tochigi, Japan) ,  Ioka Tatsuya (Department of GI Cancer Screening and Surveillance, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan) ,  Yasunami Yohichi (Islet Institute, Fukuoka University, Fukuoka, Japan) ,  Kosuge Tomoo (Department of Gastrointestinal Surgery, JR Tokyo General Hospital, Tokyo, Japan) ,  Kaneda Takashi (Department of Radiology, Nihon University School of Dentistry at Matsudo, Chiba, Japan) ,  Kato Takao (Department of Oral Implant, Nihon University School of Dentistry at Matsudo, Chiba, Japan) ,  Yagihara Kazuhiro (Department of Oral Surgery, Saitama Cancer Center, Saitama, Japan) ,  Fujita Shigeyuki (Department of Oral and Maxillofacial Surgery, Wakayama Medical University, Wakayama, Japan) ,  Yamada Tesshi (Division of Chemotherapy and Clinical Research, National Cancer Center Research Institute, Tokyo, Japan) ,  Honda Kazufumi (Division of Chemotherapy and Clinical Research, National Cancer Center Research Institute, Tokyo, Japan) ,  Honda Kazufumi (Japan Agency for Medical Research and Development (AMED) CREST, Tokyo, Japan) ,  Azuma Takeshi (Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Hyogo, Japan) ,  Yoshida Masaru (Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Hyogo, Japan) ,  Yoshida Masaru (Metabolomics Research, Department of Internal Related, Kobe University Graduate School of Medicine, Hyogo, Japan) ,  Yoshida Masaru (AMED-CREST, AMED, Hyogo, Japan)
Material： Clinica Chimica Acta  (Clin Chim Acta)
Volume： 468  Page： 98-104  Publication year： 2017 
JST Material Number： H0758A  ISSN： 0009-8981  CODEN： CCATAR  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： To improve prognosis of pancre...

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Thesaurus term： tandem mass spectrometry ,  voluntary workers ,  *biomarker ,  stable isotope ,  pancreatic tumor ,  metabolite ,  reliability(property) ,  quantitative analysis(analytical chemistry) ,  *high sensitivity ,  gas chromatography
Semi thesaurus term： 特異性 ,  糖鎖抗原 ,  診断モデル ,  *癌の早期発見 ,  *メタボロミクス , 【Automatic Indexing@JST】

Author keywords (5)： Biomarker ,  GC/MS/MS ,  Pancreatic cancer ,  Early detection ,  Metabolomics

JST classification (2)： Tumors(=neoplasms)of digestive system  (GH04000D) ,  Bioassay  (EA03060N)

Terms in the title (9)： GC ,  標的 ,  メタボロミクス ,  すい癌 ,  早期発見 ,  支援 ,  高感度 ,  バイオマーカー ,  同定