Art

J-GLOBAL ID：201802279575296670   Reference number：18A1879886

The exploration of population pharmacokinetic model for meropenem in augmented renal clearance and investigation of optimum setting of dose

過大腎クリアランスにおけるメロペネムの集団薬物動態モデルの探索と用量の最適設定の研究

Author (10)： Tamatsukuri Tatsuro (Division of Pharmacotherapeutics, Department of Clinical Pharmacy, Showa University School of Pharmacy, Tokyo, Japan) ,  Ohbayashi Masayuki (Division of Pharmacotherapeutics, Department of Clinical Pharmacy, Showa University School of Pharmacy, Tokyo, Japan) ,  Kohyama Noriko (Division of Pharmacotherapeutics, Department of Clinical Pharmacy, Showa University School of Pharmacy, Tokyo, Japan) ,  Kobayashi Yasuna (Department of Pharmacology and Therapeutics, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata, Japan) ,  Yamamoto Toshinori (Showa University Medical Foundation, Tokyo, Japan) ,  Fukuda Kenichiro (Department of Emergency, Disaster and Critical Care Medicine, Showa University, Tokyo, Japan) ,  Nakamura Shunsuke (Department of Emergency Medicine, Wakayama Rosai Hospital, Wakayama, Japan) ,  Miyake Yasufumi (Department of Emergency Medicine, Teikyo University School of Medicine, Tokyo, Japan) ,  Dohi Kenji (Department of Emergency, Disaster and Critical Care Medicine, Showa University, Tokyo, Japan) ,  Kogo Mari (Division of Pharmacotherapeutics, Department of Clinical Pharmacy, Showa University School of Pharmacy, Tokyo, Japan)
Material： Journal of Infection and Chemotherapy  (J Infect Chemother)
Volume： 24  Issue： 10  Page： 834-840  Publication year： Oct. 2018 
JST Material Number： L2852A  ISSN： 1341-321X  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *clearance ,...
Semi thesaurus term： Renal clearance ,...

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Author keywords (5)： Augmented renal clearance ,  Meropenem ,  Pharmacodynamics ,  Population pharmacokinetic analysis ,  Sepsis

JST classification (1)： Clinical biopharmacy  (GY01022L)

Substance index (1)： Meropenem

Reference (29)：

• Ministry of Health, Labour and welfare. Demographics survey in Japan, http://www.mhlw.go.jp/toukei/list/81-1a.html [accessed 22 December 2017].
• FDA. Drugs@FDA: FDA Approved Drug Products, https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=050706 [accessed 26 December 2017].
• Craig WA. The pharmacology of meropenem, a new carbapenem antibiotic. Clin Infect Dis 1997;24(Suppl. 2):S266-75.
• Shibayama T, Sugiyama D, Kamiyama E, Tokui T, Hirota T, Ikeda T. Characterization of CS-023 (RO4908463), a novel parenteral carbapenem antibiotic, and meropenem as substrates of human renal transporters. Drug Metab Pharmacokinet 2007;22:41-7.
• Udy AA, Baptista JP, Lim NL, Joynt GM, Jarrett P, Wockner L, et al. Augmented renal clearance in the ICU: results of a multicenter observational study of renal function in critically ill patients with normal plasma creatinine concentrations. Crit Care Med 2014;42:520-7.

Terms in the title (7)： 腎クリアランス ,  メロペネム ,  集団 ,  薬物動態モデル ,  探索 ,  用量 ,  研究