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J-GLOBAL ID：201802280089697020   Reference number：18A0420657

Use of CK-548 and CK-869 as Arp2/3 complex inhibitors directly suppresses microtubule assembly both in vitro and in vivo

Arp2/3複合体阻害剤としてのCK548とCK869の使用はin vitroおよびin vivoにおける微小管集合を直接抑制する【Powered by NICT】

Author (6)： Yamagishi Yuka (Department of Nanobiology, Graduate School of Advanced Integration Science, Chiba University, Chiba 263-8522, Japan) ,  Oya Kazumasa (Department of Biology, Graduate School of Science, Chiba University, Chiba 263-8522, Japan) ,  Matsuura Akira (Department of Nanobiology, Graduate School of Advanced Integration Science, Chiba University, Chiba 263-8522, Japan) ,  Matsuura Akira (Department of Biology, Graduate School of Science, Chiba University, Chiba 263-8522, Japan) ,  Abe Hiroshi (Department of Nanobiology, Graduate School of Advanced Integration Science, Chiba University, Chiba 263-8522, Japan) ,  Abe Hiroshi (Department of Biology, Graduate School of Science, Chiba University, Chiba 263-8522, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 496  Issue： 3  Page： 834-839  Publication year： 2018 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Two types of Arp2/3 complex in...

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Thesaurus term： tubulin ,  yeast ,  actin ,  cytoskeleton ,  cytoplasm ,  *microtubule ,  polymerization ,  network ,  nitrogen heterocyclic compound ,  aromatic ketone ,  carbamate ,  sulfur heterocyclic compound ,  polynuclear aromatic compound
Semi thesaurus term： 生細胞 ,  アクチン関連蛋白質3 ,  哺乳類細胞 ,  アクチン細胞骨格 ,  *阻害剤 ,  *Arp2/3 , 【Automatic Indexing@JST】

Author keywords (4)： Arp2/3 complex ,  CK-869 ,  CK-548 ,  Microtubule

JST classification (3)： Cell components in general  (EF03010Z) ,  Function of cell components  (EF03060C) ,  Enzyme in general  (EB09010D)

Substance index (1)： Nocodazole

Terms in the title (5)： Arp2 ,  複合体 ,  阻害剤 ,  微小管 ,  集合