Art

J-GLOBAL ID：201802282957486728   Reference number：18A1514131

Induced Pluripotent Stem Cells as a Model for Therapy Personalization of Pediatric Patients: Disease Modeling and Drug Adverse Effects Prevention

小児患者の治療個別化のためのモデルとしての人工多能性幹細胞:疾患モデリングと薬物有害作用予防【JST・京大機械翻訳】

Author (9)： Genova Elena (PhD School in Reproduction and Developmental Sciences, University of Trieste, Trieste, Italy) ,  Pelin Marco (Department of Life Sciences, University of Trieste, Trieste, Italy) ,  Sasaki Katsunori (Department of Histology and Embryology, Shinshu University, Matsumoto, Japan) ,  Yue Fengming (Department of Histology and Embryology, Shinshu University, Matsumoto, Japan) ,  Lanzi Gaetana (Nocivelli Institute for Molecular Medicine and Spedali Civili, Brescia, Italy) ,  Masneri Stefania (Nocivelli Institute for Molecular Medicine and Spedali Civili, Brescia, Italy) ,  Ventura Alessandro (Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy) ,  Stocco Gabriele (Department of Life Sciences, University of Trieste, Trieste, Italy) ,  Decorti Giuliana (Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy)
Material： Current Medicinal Chemistry
Volume： 25  Issue： 24  Page： 2826-2839  Publication year： 2018 
JST Material Number： W3598A  ISSN： 0929-8673  Document type： Article
Article type： 文献レビュー  Country of issue： Unknown (ARE)  Language： ENGLISH (EN)

Abstract/Point： Understanding the biological a...

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Thesaurus term： pharmacology ,  human(primates) ,  experimental disease ,  new drug ,  *induced pluripotent stem cell ,  *patient ,  *modeling ,  drug design ,  pathological state ,  *therapy
Semi thesaurus term： 有害事象 ,  リプログラミング ,  *有害作用 ,  *個性化 , 【Automatic Indexing@JST】

Author keywords (8)： Induced pluripotent stem cells ,  disease modeling ,  drug adverse effects ,  pediatric patients ,  therapy personalization ,  innovative pharmacological models ,  hepatotoxicity ,  pancreatitis.

JST classification (3)： Cell physiology in general  (EF02010S) ,  Basic neurology  (GN01020W) ,  Gene manipulation  (EC02050B)

Terms in the title (10)： 小児 ,  患者の治療 ,  個別化 ,  モデル ,  人工多能性幹細胞 ,  疾患 ,  モデリング ,  薬物 ,  有害作用 ,  予防