Art

J-GLOBAL ID：201802288042853940   Reference number：18A0952614

Long-term course of serum total and free IgE levels in severe asthma patients treated with omalizumab

オマリズマブ治療を受ける重度の喘息患者における血清総IgEレベルおよび遊離IgEレベル

Author (10)： Gon Yasuhiro (Division of Respiratory Medicine, Nihon University School of Medicine) ,  Ito Reiko (Division of Respiratory Medicine, Nihon University School of Medicine) ,  Maruoka Shuichiro (Division of Respiratory Medicine, Nihon University School of Medicine) ,  Mizumura Kenji (Division of Respiratory Medicine, Nihon University School of Medicine) ,  Kozu Yutaka (Division of Respiratory Medicine, Nihon University School of Medicine) ,  Hiranuma Hisato (Division of Respiratory Medicine, Nihon University School of Medicine) ,  Iida Yuko (Division of Respiratory Medicine, Nihon University School of Medicine) ,  Hikichi Mari (Division of Respiratory Medicine, Nihon University School of Medicine) ,  Shikano Sotaro (Division of Respiratory Medicine, Nihon University School of Medicine) ,  Hashimoto Shu (Division of Respiratory Medicine, Nihon University School of Medicine)
Material： Allergology International  (Allergol Int)
Volume： 67  Issue： 2  Page： 283-285(J-STAGE)  Publication year： 2018 
JST Material Number： L6446A  ISSN： 1323-8930  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *asthma ,...
Semi thesaurus term： *Omalizumab

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JST classification (1)： Drug therapy(=pharmacotherapy)for respiratory system diseases  (GI05020J)

Reference (9)：

• 1. Lowe PJ, Renard D. Omalizumab decreases IgE production in patients with allergic (IgE-mediated) asthma; PKPD analysis of a biomarker, total IgE. Br J Clin Pharmacol 2011;72:306-20.
• 2. Strohner P, Staatz A, Sarrach D, Steiss JO, Becher G. The recovery ELISA-a newly developed immunoassay for measurement of therapeutic antibodies and the target antigen during antibody therapy. Clin Chem Lab Med 2012;50:1263-9.
• 3. Baker DL, Peng K, Cheu M, Fischer SK. Evaluation of two commercial omalizumab/free IgE immunoassays: implications of use during therapy. Curr Med Res Opin 2014;30:913-22.
• 4. Ito R, Gon Y, Nunomura S, Atsuta R, Harada N, Hattori T, et al. Development of assay for determining free IgE levels in serum from patients treated with omalizumab. Allergol Int 2014;63:37-47.
• 5. Odajima H, Ebisawa M, Nagakura T, Fujisawa T, Akasawa A, Ito K, et al. Omalizumab in Japanese children with severe allergic asthma uncontrolled with standard therapy. Allergol Int 2015;64:364-70.

Terms in the title (7)： オマリズマブ ,  治療 ,  喘息 ,  患者 ,  血清 ,  総IgE ,  IgE